L259-0332 Screening compound: 2-{2-[(4-fluorophenyl)sulfanyl]-1H-indol-3-yl}-1-[4-(4-methoxyphenyl)piperazin-1-yl]ethan-1-one

L259-0332 Screening compound: 2-{2-[(4-fluorophenyl)sulfanyl]-1H-indol-3-yl}-1-[4-(4-methoxyphenyl)piperazin-1-yl]ethan-1-one
L259-0332 Screening compound: 2-{2-[(4-fluorophenyl)sulfanyl]-1H-indol-3-yl}-1-[4-(4-methoxyphenyl)piperazin-1-yl]ethan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound L259-0332
2-{2-[(4-fluorophenyl)sulfanyl]-1H-indol-3-yl}-1-[4-(4-methoxyphenyl)piperazin-1-yl]ethan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L259-0332

Molecular Formula

C27H26FN3O2S (C27 H26 FN3 O2 S)

Compound Name

2-{2-[(4-fluorophenyl)sulfanyl]-1H-indol-3-yl}-1-[4-(4-methoxyphenyl)piperazin-1-yl]ethan-1-one

IUPAC name

2-{2-[(4-fluorophenyl)sulfanyl]-1H-indol-3-yl}-1-[4-(4-methoxyphenyl)piperazin-1-yl]ethan-1-one

SMILES

COc(cc1)ccc1N(CC1)CCN1C(Cc(c(cccc1)c1[nH]1)c1Sc(cc1)ccc1F)=O

InChI

InChI=1S/C27H26FN3O2S/c1-33-21-10-8-20(9-11-21)30-14-16-31(17-15-30)26(32)18-24-23-4-2-3-5-25(23)29-27(24)34-22-12-6-19(28)7-13-22/h2-13,29H,14-18H2,1H3

InChI Key

QRKYQHNXXBMJEG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15121156

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

475.59

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.422

Distribution Coefficient, logD

5.422

Water Solubility, LogSw

-5.69

Polar Surface Area

36.372

Acid Dissociation Constant (pKa)

16.33

Base Dissociation Constant (pKb)

4.37

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

22.20

L259-0332 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

Indole Derivatives (10091 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with L259-0332 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L259-0332?
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What is the minimum amount of L259-0332 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L259-0332
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L259-0332
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L259-0332 available by request