L259-0347 Screening compound: 2-{2-[(4-fluorophenyl)sulfanyl]-1H-indol-3-yl}-N~1~-(2-morpholinoethyl)acetamide

L259-0347 Screening compound: 2-{2-[(4-fluorophenyl)sulfanyl]-1H-indol-3-yl}-N~1~-(2-morpholinoethyl)acetamide
L259-0347 Screening compound: 2-{2-[(4-fluorophenyl)sulfanyl]-1H-indol-3-yl}-N~1~-(2-morpholinoethyl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L259-0347
2-{2-[(4-fluorophenyl)sulfanyl]-1H-indol-3-yl}-N~1~-(2-morpholinoethyl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L259-0347

Molecular Formula

C22H24FN3O2S (C22 H24 FN3 O2 S)

Compound Name

2-{2-[(4-fluorophenyl)sulfanyl]-1H-indol-3-yl}-N~1~-(2-morpholinoethyl)acetamide

IUPAC name

n/a

SMILES

O=C(Cc(c(cccc1)c1[nH]1)c1Sc(cc1)ccc1F)NCCN1CCOCC1

InChI

InChI=1S/C22H24FN3O2S/c23-16-5-7-17(8-6-16)29-22-19(18-3-1-2-4-20(18)25-22)15-21(27)24-9-10-26-11-13-28-14-12-26/h1-8,25H,9-15H2,(H,24,27)

InChI Key

HTDMWDDNWHWJFS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15121159

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

413.52

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

2.933

Distribution Coefficient, logD

2.845

Water Solubility, LogSw

-3.31

Polar Surface Area

45.380

Acid Dissociation Constant (pKa)

13.58

Base Dissociation Constant (pKb)

6.75

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

31.82

L259-0347 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

Indole Derivatives (10091 compounds)

PI3K-Targeted Library (17255 compounds)

Antibacterial Compounds Library (13827 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Infections
  • Immune system
  • animal
Targets:
  • GPCR
  • Kinases
Mechanism of action:
  • Receptor's ligands
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with L259-0347 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L259-0347?
Check Price and Availability of L259-0347, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L259-0347 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L259-0347
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L259-0347
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L259-0347 available by request