L259-0525 Screening compound: 2-{2-[(2-fluorophenyl)sulfanyl]-1H-indol-3-yl}-1-[4-(pyridin-2-yl)piperazin-1-yl]ethan-1-one

L259-0525 Screening compound: 2-{2-[(2-fluorophenyl)sulfanyl]-1H-indol-3-yl}-1-[4-(pyridin-2-yl)piperazin-1-yl]ethan-1-one
L259-0525 Screening compound: 2-{2-[(2-fluorophenyl)sulfanyl]-1H-indol-3-yl}-1-[4-(pyridin-2-yl)piperazin-1-yl]ethan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound L259-0525
2-{2-[(2-fluorophenyl)sulfanyl]-1H-indol-3-yl}-1-[4-(pyridin-2-yl)piperazin-1-yl]ethan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L259-0525

Molecular Formula

C25H23FN4OS (C25 H23 FN4 OS)

Compound Name

2-{2-[(2-fluorophenyl)sulfanyl]-1H-indol-3-yl}-1-[4-(pyridin-2-yl)piperazin-1-yl]ethan-1-one

IUPAC name

2-{2-[(2-fluorophenyl)sulfanyl]-1H-indol-3-yl}-1-[4-(pyridin-2-yl)piperazin-1-yl]ethan-1-one

SMILES

O=C(Cc(c(cccc1)c1[nH]1)c1Sc(cccc1)c1F)N(CC1)CCN1c1ncccc1

InChI

InChI=1S/C25H23FN4OS/c26-20-8-2-4-10-22(20)32-25-19(18-7-1-3-9-21(18)28-25)17-24(31)30-15-13-29(14-16-30)23-11-5-6-12-27-23/h1-12,28H,13-17H2

InChI Key

ARWYWOGICCKLBA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15121175

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

446.55

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.808

Distribution Coefficient, logD

4.800

Water Solubility, LogSw

-4.96

Polar Surface Area

37.340

Acid Dissociation Constant (pKa)

16.33

Base Dissociation Constant (pKb)

5.71

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

20.00

L259-0525 in Drug Discovery

Included in Screening Libraries

Indole Derivatives (10091 compounds)

Targeted Diversity Library (40567 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with L259-0525 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L259-0525?
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What is the minimum amount of L259-0525 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L259-0525
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L259-0525
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L259-0525 available by request