L261-0050 Screening compound: (E)-N''-methanesulfonyl-N-(4-methoxyphenyl)-N'-(2-methylphenyl)guanidine

L261-0050 Screening compound: (E)-N''-methanesulfonyl-N-(4-methoxyphenyl)-N'-(2-methylphenyl)guanidine
L261-0050 Screening compound: (E)-N''-methanesulfonyl-N-(4-methoxyphenyl)-N'-(2-methylphenyl)guanidine alternative view

Chemical Structure Depiction of ChemDiv screening compound L261-0050
(E)-N''-methanesulfonyl-N-(4-methoxyphenyl)-N'-(2-methylphenyl)guanidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L261-0050

Molecular Formula

C16H19N3O3S (C16 H19 N3 O3 S)

Compound Name

(E)-N''-methanesulfonyl-N-(4-methoxyphenyl)-N'-(2-methylphenyl)guanidine

IUPAC name

(E)-N''-methanesulfonyl-N-(4-methoxyphenyl)-N'-(2-methylphenyl)guanidine

SMILES

Cc(cccc1)c1N/C(/Nc(cc1)ccc1OC)=N/S(C)(=O)=O

InChI

InChI=1S/C16H19N3O3S/c1-12-6-4-5-7-15(12)18-16(19-23(3,20)21)17-13-8-10-14(22-2)11-9-13/h4-11H,1-3H3,(H2,17,18,19)

InChI Key

KNBUZYJFMUXRCV-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15121263

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

333.41

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.947

Distribution Coefficient, logD

2.947

Water Solubility, LogSw

-3.47

Polar Surface Area

65.894

Acid Dissociation Constant (pKa)

12.67

Base Dissociation Constant (pKb)

2.53

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

18.75

L261-0050 in Drug Discovery

Included in Screening Libraries

Cardiovascular Library (22201 compounds)

Glucocorticoid receptors Library (4806 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cardiovascular
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
  • Endocrine
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Nuclear receptors
  • Proteases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L261-0050 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L261-0050?
Check Price and Availability of L261-0050, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L261-0050 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L261-0050
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L261-0050
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L261-0050 available by request