L262-1075 Screening compound: 4-[6-(5-fluoro-2-methoxyphenyl)-4-pyrimidinyl]-N-(4-methylbenzyl)tetrahydro-1(2H)-pyrazinecarboxamide

L262-1075 Screening compound: 4-[6-(5-fluoro-2-methoxyphenyl)-4-pyrimidinyl]-N-(4-methylbenzyl)tetrahydro-1(2H)-pyrazinecarboxamide
L262-1075 Screening compound: 4-[6-(5-fluoro-2-methoxyphenyl)-4-pyrimidinyl]-N-(4-methylbenzyl)tetrahydro-1(2H)-pyrazinecarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L262-1075
4-[6-(5-fluoro-2-methoxyphenyl)-4-pyrimidinyl]-N-(4-methylbenzyl)tetrahydro-1(2H)-pyrazinecarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L262-1075

Molecular Formula

C24H26FN5O2 (C24 H26 FN5 O2)

Compound Name

4-[6-(5-fluoro-2-methoxyphenyl)-4-pyrimidinyl]-N-(4-methylbenzyl)tetrahydro-1(2H)-pyrazinecarboxamide

IUPAC name

4-[6-(5-fluoro-2-methoxyphenyl)pyrimidin-4-yl]-N-[(4-methylphenyl)methyl]piperazine-1-carboxamide

SMILES

Cc1ccc(CNC(N(CC2)CCN2c2cc(-c(cc(cc3)F)c3OC)ncn2)=O)cc1

InChI

InChI=1S/C24H26FN5O2/c1-17-3-5-18(6-4-17)15-26-24(31)30-11-9-29(10-12-30)23-14-21(27-16-28-23)20-13-19(25)7-8-22(20)32-2/h3-8,13-14,16H,9-12,15H2,1-2H3,(H,26,31)

InChI Key

OWZPOWGKTUFQAI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27238840

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

435.5

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.213

Distribution Coefficient, logD

4.211

Water Solubility, LogSw

-4.23

Polar Surface Area

56.922

Acid Dissociation Constant (pKa)

14.51

Base Dissociation Constant (pKb)

5.09

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

29.17

L262-1075 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Indoleamine 2,3-dioxygenase 1 Focused Library (5816 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Digestive system
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Immune system
Targets:
  • Others

References: we are preparing a list of scientific research reports with L262-1075 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L262-1075?
Check Price and Availability of L262-1075, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L262-1075 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L262-1075
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L262-1075
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L262-1075 available by request