L266-0458 Screening compound: N-{3-[2-(1H-1,3-benzodiazol-2-yl)ethyl]phenyl}-2-fluorobenzene-1-sulfonamide

L266-0458 Screening compound: N-{3-[2-(1H-1,3-benzodiazol-2-yl)ethyl]phenyl}-2-fluorobenzene-1-sulfonamide
L266-0458 Screening compound: N-{3-[2-(1H-1,3-benzodiazol-2-yl)ethyl]phenyl}-2-fluorobenzene-1-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L266-0458
N-{3-[2-(1H-1,3-benzodiazol-2-yl)ethyl]phenyl}-2-fluorobenzene-1-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L266-0458

Molecular Formula

C21H18FN3O2S (C21 H18 FN3 O2 S)

Compound Name

N-{3-[2-(1H-1,3-benzodiazol-2-yl)ethyl]phenyl}-2-fluorobenzene-1-sulfonamide

IUPAC name

N-{3-[2-(1H-13-benzodiazol-2-yl)ethyl]phenyl}-2-fluorobenzene-1-sulfonamide

SMILES

O=S(c(cccc1)c1F)(Nc1cc(CCc2nc(cccc3)c3[nH]2)ccc1)=O

InChI

InChI=1S/C21H18FN3O2S/c22-17-8-1-4-11-20(17)28(26,27)25-16-7-5-6-15(14-16)12-13-21-23-18-9-2-3-10-19(18)24-21/h1-11,14,25H,12-13H2,(H,23,24)

InChI Key

GIKXLWHQCDOEDD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15121868

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

395.46

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.477

Distribution Coefficient, logD

4.441

Water Solubility, LogSw

-4.55

Polar Surface Area

60.898

Acid Dissociation Constant (pKa)

9.03

Base Dissociation Constant (pKb)

6.18

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

9.50

L266-0458 in Drug Discovery

Included in Screening Libraries

CNS Targets (44014 compounds)

Neuropeptide S Library (2850 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Digestive system
  • Nervous system
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L266-0458 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L266-0458?
Check Price and Availability of L266-0458, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L266-0458 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L266-0458
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L266-0458
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L266-0458 available by request