L267-0224 Screening compound: 2,4,5-trimethyl-N~1~-{4-[2-(1-methyl-1H-1,3-benzimidazol-2-yl)ethyl]phenyl}-1-benzenesulfonamide

L267-0224 Screening compound: 2,4,5-trimethyl-N~1~-{4-[2-(1-methyl-1H-1,3-benzimidazol-2-yl)ethyl]phenyl}-1-benzenesulfonamide
L267-0224 Screening compound: 2,4,5-trimethyl-N~1~-{4-[2-(1-methyl-1H-1,3-benzimidazol-2-yl)ethyl]phenyl}-1-benzenesulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L267-0224
2,4,5-trimethyl-N~1~-{4-[2-(1-methyl-1H-1,3-benzimidazol-2-yl)ethyl]phenyl}-1-benzenesulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L267-0224

Molecular Formula

C25H27N3O2S (C25 H27 N3 O2 S)

Compound Name

2,4,5-trimethyl-N~1~-{4-[2-(1-methyl-1H-1,3-benzimidazol-2-yl)ethyl]phenyl}-1-benzenesulfonamide

IUPAC name

245-trimethyl-N-{4-[2-(1-methyl-1H-13-benzodiazol-2-yl)ethyl]phenyl}benzene-1-sulfonamide

SMILES

Cc(c(C)c1)cc(C)c1S(Nc1ccc(CCc2nc(cccc3)c3n2C)cc1)(=O)=O

InChI

InChI=1S/C25H27N3O2S/c1-17-15-19(3)24(16-18(17)2)31(29,30)27-21-12-9-20(10-13-21)11-14-25-26-22-7-5-6-8-23(22)28(25)4/h5-10,12-13,15-16,27H,11,14H2,1-4H3

InChI Key

PUMIXBLDGHXTSB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15121947

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

433.57

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

6.001

Distribution Coefficient, logD

5.776

Water Solubility, LogSw

-5.56

Polar Surface Area

52.603

Acid Dissociation Constant (pKa)

7.99

Base Dissociation Constant (pKb)

6.92

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

24.00

L267-0224 in Drug Discovery

Included in Screening Libraries

CNS Targets (44014 compounds)

Glucocorticoid receptors Library (4806 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
  • Endocrine
Targets:
  • Nuclear receptors
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L267-0224 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L267-0224?
Check Price and Availability of L267-0224, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L267-0224 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L267-0224
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L267-0224
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L267-0224 available by request