L267-1118 Screening compound: 2,4-dimethyl-N-{4-[2-(1-phenyl-1H-1,3-benzodiazol-2-yl)ethyl]phenyl}benzene-1-sulfonamide

L267-1118 Screening compound: 2,4-dimethyl-N-{4-[2-(1-phenyl-1H-1,3-benzodiazol-2-yl)ethyl]phenyl}benzene-1-sulfonamide
L267-1118 Screening compound: 2,4-dimethyl-N-{4-[2-(1-phenyl-1H-1,3-benzodiazol-2-yl)ethyl]phenyl}benzene-1-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L267-1118
2,4-dimethyl-N-{4-[2-(1-phenyl-1H-1,3-benzodiazol-2-yl)ethyl]phenyl}benzene-1-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L267-1118

Molecular Formula

C29H27N3O2S (C29 H27 N3 O2 S)

Compound Name

2,4-dimethyl-N-{4-[2-(1-phenyl-1H-1,3-benzodiazol-2-yl)ethyl]phenyl}benzene-1-sulfonamide

IUPAC name

24-dimethyl-N-{4-[2-(1-phenyl-1H-13-benzodiazol-2-yl)ethyl]phenyl}benzene-1-sulfonamide

SMILES

Cc(cc1)cc(C)c1S(Nc1ccc(CCc2nc(cccc3)c3n2-c2ccccc2)cc1)(=O)=O

InChI

InChI=1S/C29H27N3O2S/c1-21-12-18-28(22(2)20-21)35(33,34)31-24-16-13-23(14-17-24)15-19-29-30-26-10-6-7-11-27(26)32(29)25-8-4-3-5-9-25/h3-14,16-18,20,31H,15,19H2,1-2H3

InChI Key

ABMGKPIZWRYLAC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15122022

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

481.62

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

6.916

Distribution Coefficient, logD

6.763

Water Solubility, LogSw

-5.78

Polar Surface Area

52.265

Acid Dissociation Constant (pKa)

7.99

Base Dissociation Constant (pKb)

6.50

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

13.80

L267-1118 in Drug Discovery

Included in Screening Libraries

Glucocorticoid receptors Library (4806 compounds)

PI3K-Targeted Library (17255 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Nuclear receptors
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L267-1118 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L267-1118?
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What is the minimum amount of L267-1118 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L267-1118
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L267-1118
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L267-1118 available by request