L273-0181 Screening compound: N1-[5-(azepane-1-sulfonyl)thiophen-2-yl]-N3-(propan-2-yl)piperidine-1,3-dicarboxamide

L273-0181 Screening compound: N1-[5-(azepane-1-sulfonyl)thiophen-2-yl]-N3-(propan-2-yl)piperidine-1,3-dicarboxamide
L273-0181 Screening compound: N1-[5-(azepane-1-sulfonyl)thiophen-2-yl]-N3-(propan-2-yl)piperidine-1,3-dicarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L273-0181
N1-[5-(azepane-1-sulfonyl)thiophen-2-yl]-N3-(propan-2-yl)piperidine-1,3-dicarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L273-0181

Molecular Formula

C20H32N4O4S2 (C20 H32 N4 O4 S2)

Compound Name

N1-[5-(azepane-1-sulfonyl)thiophen-2-yl]-N3-(propan-2-yl)piperidine-1,3-dicarboxamide

IUPAC name

N1-[5-(azepane-1-sulfonyl)thiophen-2-yl]-N3-(propan-2-yl)piperidine-13-dicarboxamide

SMILES

CC(C)NC(C(CCC1)CN1C(Nc(s1)ccc1S(N1CCCCCC1)(=O)=O)=O)=O

InChI

InChI=1S/C20H32N4O4S2/c1-15(2)21-19(25)16-8-7-11-23(14-16)20(26)22-17-9-10-18(29-17)30(27,28)24-12-5-3-4-6-13-24/h9-10,15-16H,3-8,11-14H2,1-2H3,(H,21,25)(H,22,26)/t16-/m0/s1

InChI Key

DOLKBAOGKGPGMH-INIZCTEOSA-N

MDL Number (MFCD)

MFCD15122418

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

456.63

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.554

Distribution Coefficient, logD

2.554

Water Solubility, LogSw

-2.98

Polar Surface Area

81.834

Acid Dissociation Constant (pKa)

10.36

Base Dissociation Constant (pKb)

1.17

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

70.00

L273-0181 in Drug Discovery

Included in Screening Libraries

Autophagy-Targeted Library (4564 compounds)

SmartTM Library (51161 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system

References: we are preparing a list of scientific research reports with L273-0181 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L273-0181?
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What is the minimum amount of L273-0181 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L273-0181
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L273-0181
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L273-0181 available by request