L273-0230 Screening compound: N-{5-[(DIMETHYLAMINO)SULFONYL]-2-THIENYL}-N-(3-FLUOROPHENYL)TETRAHYDRO-1,3(2H)-PYRIDINEDICARBOXAMIDE

L273-0230 Screening compound: N-{5-[(DIMETHYLAMINO)SULFONYL]-2-THIENYL}-N-(3-FLUOROPHENYL)TETRAHYDRO-1,3(2H)-PYRIDINEDICARBOXAMIDE
L273-0230 Screening compound: N-{5-[(DIMETHYLAMINO)SULFONYL]-2-THIENYL}-N-(3-FLUOROPHENYL)TETRAHYDRO-1,3(2H)-PYRIDINEDICARBOXAMIDE alternative view

Chemical Structure Depiction of ChemDiv screening compound L273-0230
N-{5-[(DIMETHYLAMINO)SULFONYL]-2-THIENYL}-N-(3-FLUOROPHENYL)TETRAHYDRO-1,3(2H)-PYRIDINEDICARBOXAMIDE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L273-0230

Molecular Formula

C19H23FN4O4S2 (C19 H23 FN4 O4 S2)

Compound Name

N-{5-[(DIMETHYLAMINO)SULFONYL]-2-THIENYL}-N-(3-FLUOROPHENYL)TETRAHYDRO-1,3(2H)-PYRIDINEDICARBOXAMIDE

IUPAC name

n/a

SMILES

CN(C)S(c1ccc(NC(N(CCC2)CC2C(Nc2cc(F)ccc2)=O)=O)s1)(=O)=O

InChI

InChI=1S/C19H23FN4O4S2/c1-23(2)30(27,28)17-9-8-16(29-17)22-19(26)24-10-4-5-13(12-24)18(25)21-15-7-3-6-14(20)11-15/h3,6-9,11,13H,4-5,10,12H2,1-2H3,(H,21,25)(H,22,26)/t13-/m0/s1

InChI Key

PFUVDVAFZPAGOO-ZDUSSCGKSA-N

MDL Number (MFCD)

MFCD15122423

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

454.55

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.384

Distribution Coefficient, logD

2.383

Water Solubility, LogSw

-3.03

Polar Surface Area

82.888

Acid Dissociation Constant (pKa)

10.12

Base Dissociation Constant (pKb)

-0.23

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

36.80

L273-0230 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with L273-0230 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L273-0230?
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What is the minimum amount of L273-0230 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L273-0230
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L273-0230
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L273-0230 available by request