L273-0368 Screening compound: N3-(4-chlorophenyl)-N1-[5-(diethylsulfamoyl)thiophen-2-yl]piperidine-1,3-dicarboxamide

L273-0368 Screening compound: N3-(4-chlorophenyl)-N1-[5-(diethylsulfamoyl)thiophen-2-yl]piperidine-1,3-dicarboxamide
L273-0368 Screening compound: N3-(4-chlorophenyl)-N1-[5-(diethylsulfamoyl)thiophen-2-yl]piperidine-1,3-dicarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L273-0368
N3-(4-chlorophenyl)-N1-[5-(diethylsulfamoyl)thiophen-2-yl]piperidine-1,3-dicarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L273-0368

Molecular Formula

C21H27ClN4O4S2 (C21 H27 ClN4 O4 S2)

Compound Name

N3-(4-chlorophenyl)-N1-[5-(diethylsulfamoyl)thiophen-2-yl]piperidine-1,3-dicarboxamide

IUPAC name

N3-(4-chlorophenyl)-N1-[5-(diethylsulfamoyl)thiophen-2-yl]piperidine-13-dicarboxamide

SMILES

CCN(CC)S(c1ccc(NC(N(CCC2)CC2C(Nc(cc2)ccc2Cl)=O)=O)s1)(=O)=O

InChI

InChI=1S/C21H27ClN4O4S2/c1-3-26(4-2)32(29,30)19-12-11-18(31-19)24-21(28)25-13-5-6-15(14-25)20(27)23-17-9-7-16(22)8-10-17/h7-12,15H,3-6,13-14H2,1-2H3,(H,23,27)(H,24,28)/t15-/m0/s1

InChI Key

BQEYYBJVMOHOGL-HNNXBMFYSA-N

MDL Number (MFCD)

MFCD27238998

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

499.05

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.437

Distribution Coefficient, logD

3.437

Water Solubility, LogSw

-3.82

Polar Surface Area

80.321

Acid Dissociation Constant (pKa)

10.21

Base Dissociation Constant (pKb)

-0.17

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

42.90

L273-0368 in Drug Discovery

Included in Screening Libraries

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

SmartTM Library (51161 compounds)

Targeted Diversity Library (40567 compounds)

New Agro Library (44492 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Mimetics
Agro:
  • Agro

References: we are preparing a list of scientific research reports with L273-0368 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L273-0368?
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What is the minimum amount of L273-0368 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L273-0368
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L273-0368
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L273-0368 available by request