L275-0160 Screening compound: 1-(4-{[1-methyl-5-(pyrrolidine-1-carbonyl)-1H-1,3-benzodiazol-2-yl]methyl}piperazin-1-yl)-2-phenoxyethan-1-one

L275-0160 Screening compound: 1-(4-{[1-methyl-5-(pyrrolidine-1-carbonyl)-1H-1,3-benzodiazol-2-yl]methyl}piperazin-1-yl)-2-phenoxyethan-1-one
L275-0160 Screening compound: 1-(4-{[1-methyl-5-(pyrrolidine-1-carbonyl)-1H-1,3-benzodiazol-2-yl]methyl}piperazin-1-yl)-2-phenoxyethan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound L275-0160
1-(4-{[1-methyl-5-(pyrrolidine-1-carbonyl)-1H-1,3-benzodiazol-2-yl]methyl}piperazin-1-yl)-2-phenoxyethan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L275-0160

Molecular Formula

C26H31N5O3 (C26 H31 N5 O3)

Compound Name

1-(4-{[1-methyl-5-(pyrrolidine-1-carbonyl)-1H-1,3-benzodiazol-2-yl]methyl}piperazin-1-yl)-2-phenoxyethan-1-one

IUPAC name

1-(4-{[1-methyl-5-(pyrrolidine-1-carbonyl)-1H-13-benzodiazol-2-yl]methyl}piperazin-1-yl)-2-phenoxyethan-1-one

SMILES

Cn1c(ccc(C(N2CCCC2)=O)c2)c2nc1CN(CC1)CCN1C(COc1ccccc1)=O

InChI

InChI=1S/C26H31N5O3/c1-28-23-10-9-20(26(33)31-11-5-6-12-31)17-22(23)27-24(28)18-29-13-15-30(16-14-29)25(32)19-34-21-7-3-2-4-8-21/h2-4,7-10,17H,5-6,11-16,18-19H2,1H3

InChI Key

VFMDNQUCCDTYKD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27239033

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

461.56

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

1.456

Distribution Coefficient, logD

1.012

Water Solubility, LogSw

-2.00

Polar Surface Area

56.400

Acid Dissociation Constant (pKa)

25.23

Base Dissociation Constant (pKb)

7.65

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

42.30

L275-0160 in Drug Discovery

Included in Screening Libraries

PI3K-Targeted Library (17255 compounds)

Protein-Protein Interaction Library (218420 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Immune system
Targets:
  • Kinases
Mechanism of action:
  • PPI modulators
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L275-0160 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L275-0160?
Check Price and Availability of L275-0160, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L275-0160 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L275-0160
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L275-0160
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L275-0160 available by request