L277-0200 Screening compound: 2-({4-[(2-chloro-4-methylphenyl)carbamoyl]piperazin-1-yl}methyl)-1-ethyl-N,N-dimethyl-1H-1,3-benzodiazole-5-carboxamide

L277-0200 Screening compound: 2-({4-[(2-chloro-4-methylphenyl)carbamoyl]piperazin-1-yl}methyl)-1-ethyl-N,N-dimethyl-1H-1,3-benzodiazole-5-carboxamide
L277-0200 Screening compound: 2-({4-[(2-chloro-4-methylphenyl)carbamoyl]piperazin-1-yl}methyl)-1-ethyl-N,N-dimethyl-1H-1,3-benzodiazole-5-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L277-0200
2-({4-[(2-chloro-4-methylphenyl)carbamoyl]piperazin-1-yl}methyl)-1-ethyl-N,N-dimethyl-1H-1,3-benzodiazole-5-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L277-0200

Molecular Formula

C25H31ClN6O2 (C25 H31 ClN6 O2)

Compound Name

2-({4-[(2-chloro-4-methylphenyl)carbamoyl]piperazin-1-yl}methyl)-1-ethyl-N,N-dimethyl-1H-1,3-benzodiazole-5-carboxamide

IUPAC name

2-({4-[(2-chloro-4-methylphenyl)carbamoyl]piperazin-1-yl}methyl)-1-ethyl-NN-dimethyl-1H-13-benzodiazole-5-carboxamide

SMILES

CCn1c(ccc(C(N(C)C)=O)c2)c2nc1CN(CC1)CCN1C(Nc(ccc(C)c1)c1Cl)=O

InChI

InChI=1S/C25H31ClN6O2/c1-5-32-22-9-7-18(24(33)29(3)4)15-21(22)27-23(32)16-30-10-12-31(13-11-30)25(34)28-20-8-6-17(2)14-19(20)26/h6-9,14-15H,5,10-13,16H2,1-4H3,(H,28,34)

InChI Key

KEYMTBYLBZAMQR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27239165

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

483.01

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.795

Distribution Coefficient, logD

2.713

Water Solubility, LogSw

-3.52

Polar Surface Area

55.452

Acid Dissociation Constant (pKa)

12.02

Base Dissociation Constant (pKb)

6.72

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

40.00

L277-0200 in Drug Discovery

Included in Screening Libraries

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with L277-0200 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L277-0200?
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What is the minimum amount of L277-0200 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L277-0200
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L277-0200
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L277-0200 available by request