L277-0219 Screening compound: 1-ethyl-2-({4-[(4-fluorophenyl)carbamoyl]piperazin-1-yl}methyl)-N,N-dimethyl-1H-1,3-benzodiazole-5-carboxamide

L277-0219 Screening compound: 1-ethyl-2-({4-[(4-fluorophenyl)carbamoyl]piperazin-1-yl}methyl)-N,N-dimethyl-1H-1,3-benzodiazole-5-carboxamide
L277-0219 Screening compound: 1-ethyl-2-({4-[(4-fluorophenyl)carbamoyl]piperazin-1-yl}methyl)-N,N-dimethyl-1H-1,3-benzodiazole-5-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L277-0219
1-ethyl-2-({4-[(4-fluorophenyl)carbamoyl]piperazin-1-yl}methyl)-N,N-dimethyl-1H-1,3-benzodiazole-5-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L277-0219

Molecular Formula

C24H29FN6O2 (C24 H29 FN6 O2)

Compound Name

1-ethyl-2-({4-[(4-fluorophenyl)carbamoyl]piperazin-1-yl}methyl)-N,N-dimethyl-1H-1,3-benzodiazole-5-carboxamide

IUPAC name

1-ethyl-2-({4-[(4-fluorophenyl)carbamoyl]piperazin-1-yl}methyl)-NN-dimethyl-1H-13-benzodiazole-5-carboxamide

SMILES

CCn1c(ccc(C(N(C)C)=O)c2)c2nc1CN(CC1)CCN1C(Nc(cc1)ccc1F)=O

InChI

InChI=1S/C24H29FN6O2/c1-4-31-21-10-5-17(23(32)28(2)3)15-20(21)27-22(31)16-29-11-13-30(14-12-29)24(33)26-19-8-6-18(25)7-9-19/h5-10,15H,4,11-14,16H2,1-3H3,(H,26,33)

InChI Key

LWPMUQAYPSLIOJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27239179

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

452.53

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

1.705

Distribution Coefficient, logD

1.623

Water Solubility, LogSw

-2.49

Polar Surface Area

56.150

Acid Dissociation Constant (pKa)

12.23

Base Dissociation Constant (pKb)

6.72

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

37.50

L277-0219 in Drug Discovery

Included in Screening Libraries

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with L277-0219 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L277-0219?
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What is the minimum amount of L277-0219 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L277-0219
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L277-0219
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L277-0219 available by request