L277-0250 Screening compound: ethyl 3-[(4-{[5-(dimethylcarbamoyl)-1-ethyl-1H-1,3-benzodiazol-2-yl]methyl}piperazine-1-carbonyl)amino]propanoate

L277-0250 Screening compound: ethyl 3-[(4-{[5-(dimethylcarbamoyl)-1-ethyl-1H-1,3-benzodiazol-2-yl]methyl}piperazine-1-carbonyl)amino]propanoate
L277-0250 Screening compound: ethyl 3-[(4-{[5-(dimethylcarbamoyl)-1-ethyl-1H-1,3-benzodiazol-2-yl]methyl}piperazine-1-carbonyl)amino]propanoate alternative view

Chemical Structure Depiction of ChemDiv screening compound L277-0250
ethyl 3-[(4-{[5-(dimethylcarbamoyl)-1-ethyl-1H-1,3-benzodiazol-2-yl]methyl}piperazine-1-carbonyl)amino]propanoate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L277-0250

Molecular Formula

C23H34N6O4 (C23 H34 N6 O4)

Compound Name

ethyl 3-[(4-{[5-(dimethylcarbamoyl)-1-ethyl-1H-1,3-benzodiazol-2-yl]methyl}piperazine-1-carbonyl)amino]propanoate

IUPAC name

ethyl 3-[(4-{[5-(dimethylcarbamoyl)-1-ethyl-1H-13-benzodiazol-2-yl]methyl}piperazine-1-carbonyl)amino]propanoate

SMILES

CCn1c(ccc(C(N(C)C)=O)c2)c2nc1CN(CC1)CCN1C(NCCC(OCC)=O)=O

InChI

InChI=1S/C23H34N6O4/c1-5-29-19-8-7-17(22(31)26(3)4)15-18(19)25-20(29)16-27-11-13-28(14-12-27)23(32)24-10-9-21(30)33-6-2/h7-8,15H,5-6,9-14,16H2,1-4H3,(H,24,32)

InChI Key

GJFGDQWEMLVWGG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27239199

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

458.56

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

12.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

0.418

Distribution Coefficient, logD

0.336

Water Solubility, LogSw

-2.15

Polar Surface Area

77.744

Acid Dissociation Constant (pKa)

16.56

Base Dissociation Constant (pKb)

6.72

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

56.50

L277-0250 in Drug Discovery

Included in Screening Libraries

PI3K-Targeted Library (17255 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with L277-0250 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L277-0250?
Check Price and Availability of L277-0250, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L277-0250 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L277-0250
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L277-0250
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L277-0250 available by request