L277-0258 Screening compound: 2-({4-[(2-methoxyphenyl)carbamoyl]piperazin-1-yl}methyl)-N,N,1-trimethyl-1H-1,3-benzodiazole-5-carboxamide

L277-0258 Screening compound: 2-({4-[(2-methoxyphenyl)carbamoyl]piperazin-1-yl}methyl)-N,N,1-trimethyl-1H-1,3-benzodiazole-5-carboxamide
L277-0258 Screening compound: 2-({4-[(2-methoxyphenyl)carbamoyl]piperazin-1-yl}methyl)-N,N,1-trimethyl-1H-1,3-benzodiazole-5-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L277-0258
2-({4-[(2-methoxyphenyl)carbamoyl]piperazin-1-yl}methyl)-N,N,1-trimethyl-1H-1,3-benzodiazole-5-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L277-0258

Molecular Formula

C24H30N6O3 (C24 H30 N6 O3)

Compound Name

2-({4-[(2-methoxyphenyl)carbamoyl]piperazin-1-yl}methyl)-N,N,1-trimethyl-1H-1,3-benzodiazole-5-carboxamide

IUPAC name

2-({4-[(2-methoxyphenyl)carbamoyl]piperazin-1-yl}methyl)-NN1-trimethyl-1H-13-benzodiazole-5-carboxamide

SMILES

CN(C)C(c(cc1)cc2c1n(C)c(CN(CC1)CCN1C(Nc(cccc1)c1OC)=O)n2)=O

InChI

InChI=1S/C24H30N6O3/c1-27(2)23(31)17-9-10-20-19(15-17)25-22(28(20)3)16-29-11-13-30(14-12-29)24(32)26-18-7-5-6-8-21(18)33-4/h5-10,15H,11-14,16H2,1-4H3,(H,26,32)

InChI Key

DUQDDFLJVXSJDD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27239202

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

450.54

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

1.185

Distribution Coefficient, logD

0.740

Water Solubility, LogSw

-2.33

Polar Surface Area

64.168

Acid Dissociation Constant (pKa)

12.58

Base Dissociation Constant (pKb)

7.65

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

37.50

L277-0258 in Drug Discovery

Included in Screening Libraries

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with L277-0258 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L277-0258?
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What is the minimum amount of L277-0258 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L277-0258
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L277-0258
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L277-0258 available by request