L277-0269 Screening compound: 2-({4-[(3,4-dimethylphenyl)carbamoyl]piperazin-1-yl}methyl)-N,N,1-trimethyl-1H-1,3-benzodiazole-5-carboxamide

L277-0269 Screening compound: 2-({4-[(3,4-dimethylphenyl)carbamoyl]piperazin-1-yl}methyl)-N,N,1-trimethyl-1H-1,3-benzodiazole-5-carboxamide
L277-0269 Screening compound: 2-({4-[(3,4-dimethylphenyl)carbamoyl]piperazin-1-yl}methyl)-N,N,1-trimethyl-1H-1,3-benzodiazole-5-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L277-0269
2-({4-[(3,4-dimethylphenyl)carbamoyl]piperazin-1-yl}methyl)-N,N,1-trimethyl-1H-1,3-benzodiazole-5-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L277-0269

Molecular Formula

C25H32N6O2 (C25 H32 N6 O2)

Compound Name

2-({4-[(3,4-dimethylphenyl)carbamoyl]piperazin-1-yl}methyl)-N,N,1-trimethyl-1H-1,3-benzodiazole-5-carboxamide

IUPAC name

2-({4-[(34-dimethylphenyl)carbamoyl]piperazin-1-yl}methyl)-NN1-trimethyl-1H-13-benzodiazole-5-carboxamide

SMILES

Cc(cc1)c(C)cc1NC(N1CCN(Cc2nc(cc(cc3)C(N(C)C)=O)c3n2C)CC1)=O

InChI

InChI=1S/C25H32N6O2/c1-17-6-8-20(14-18(17)2)26-25(33)31-12-10-30(11-13-31)16-23-27-21-15-19(24(32)28(3)4)7-9-22(21)29(23)5/h6-9,14-15H,10-13,16H2,1-5H3,(H,26,33)

InChI Key

AWVFGBQTQBKONM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27239211

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

448.57

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.023

Distribution Coefficient, logD

1.579

Water Solubility, LogSw

-2.71

Polar Surface Area

57.235

Acid Dissociation Constant (pKa)

14.09

Base Dissociation Constant (pKb)

7.65

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

40.00

L277-0269 in Drug Discovery

Included in Screening Libraries

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with L277-0269 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L277-0269?
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What is the minimum amount of L277-0269 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L277-0269
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L277-0269
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L277-0269 available by request