L280-2289 Screening compound: 3-[4-methyl-3-(piperidine-1-sulfonyl)phenyl]-N-(pyridin-2-yl)-1,2,4-oxadiazole-5-carboxamide

L280-2289 Screening compound: 3-[4-methyl-3-(piperidine-1-sulfonyl)phenyl]-N-(pyridin-2-yl)-1,2,4-oxadiazole-5-carboxamide
L280-2289 Screening compound: 3-[4-methyl-3-(piperidine-1-sulfonyl)phenyl]-N-(pyridin-2-yl)-1,2,4-oxadiazole-5-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L280-2289
3-[4-methyl-3-(piperidine-1-sulfonyl)phenyl]-N-(pyridin-2-yl)-1,2,4-oxadiazole-5-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L280-2289

Molecular Formula

C20H21N5O4S (C20 H21 N5 O4 S)

Compound Name

3-[4-methyl-3-(piperidine-1-sulfonyl)phenyl]-N-(pyridin-2-yl)-1,2,4-oxadiazole-5-carboxamide

IUPAC name

3-[4-methyl-3-(piperidine-1-sulfonyl)phenyl]-N-(pyridin-2-yl)-124-oxadiazole-5-carboxamide

SMILES

Cc(ccc(-c1noc(C(Nc2ncccc2)=O)n1)c1)c1S(N1CCCCC1)(=O)=O

InChI

InChI=1S/C20H21N5O4S/c1-14-8-9-15(13-16(14)30(27,28)25-11-5-2-6-12-25)18-23-20(29-24-18)19(26)22-17-7-3-4-10-21-17/h3-4,7-10,13H,2,5-6,11-12H2,1H3,(H,21,22,26)

InChI Key

IBHDXWRJIUEPKC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27239626

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

427.48

Hydrogen Bond Acceptors Count

11.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

3.701

Distribution Coefficient, logD

3.697

Water Solubility, LogSw

-3.81

Polar Surface Area

96.333

Acid Dissociation Constant (pKa)

9.44

Base Dissociation Constant (pKb)

2.55

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

30.00

L280-2289 in Drug Discovery

Included in Screening Libraries

Angiogenesis library (14822 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Akt-Targeted Library (14764 compounds)

Anti-HIV1 Library (19540 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Antiviral
  • Infections
  • Immune system
Targets:
  • Kinases
  • Kinases

References: we are preparing a list of scientific research reports with L280-2289 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L280-2289?
Check Price and Availability of L280-2289, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L280-2289 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L280-2289
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L280-2289
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L280-2289 available by request