L281-0034 Screening compound: 2,6-dimethoxy-N-[4-({5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl}sulfanyl)phenyl]benzamide

L281-0034 Screening compound: 2,6-dimethoxy-N-[4-({5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl}sulfanyl)phenyl]benzamide
L281-0034 Screening compound: 2,6-dimethoxy-N-[4-({5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl}sulfanyl)phenyl]benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L281-0034
2,6-dimethoxy-N-[4-({5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl}sulfanyl)phenyl]benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L281-0034

Molecular Formula

C21H19N5O3S (C21 H19 N5 O3 S)

Compound Name

2,6-dimethoxy-N-[4-({5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl}sulfanyl)phenyl]benzamide

IUPAC name

26-dimethoxy-N-[4-({5-methyl-[124]triazolo[15-a]pyrimidin-7-yl}sulfanyl)phenyl]benzamide

SMILES

Cc1nc2ncnn2c(Sc(cc2)ccc2NC(c(c(OC)ccc2)c2OC)=O)c1

InChI

InChI=1S/C21H19N5O3S/c1-13-11-18(26-21(24-13)22-12-23-26)30-15-9-7-14(8-10-15)25-20(27)19-16(28-2)5-4-6-17(19)29-3/h4-12H,1-3H3,(H,25,27)

InChI Key

VLMBXCHSQDNCDD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15122491

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

421.48

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.982

Distribution Coefficient, logD

2.948

Water Solubility, LogSw

-3.51

Polar Surface Area

70.101

Acid Dissociation Constant (pKa)

8.49

Base Dissociation Constant (pKb)

3.09

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

14.30

L281-0034 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with L281-0034 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L281-0034?
Check Price and Availability of L281-0034, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L281-0034 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L281-0034
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L281-0034
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L281-0034 available by request