L282-0052 Screening compound: 3-(4-bromo-3-methylphenyl)-1-[4-({5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl}sulfanyl)phenyl]urea

L282-0052 Screening compound: 3-(4-bromo-3-methylphenyl)-1-[4-({5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl}sulfanyl)phenyl]urea
L282-0052 Screening compound: 3-(4-bromo-3-methylphenyl)-1-[4-({5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl}sulfanyl)phenyl]urea alternative view

Chemical Structure Depiction of ChemDiv screening compound L282-0052
3-(4-bromo-3-methylphenyl)-1-[4-({5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl}sulfanyl)phenyl]urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L282-0052

Molecular Formula

C20H17BrN6OS (C20 H17 BrN6 OS)

Compound Name

3-(4-bromo-3-methylphenyl)-1-[4-({5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl}sulfanyl)phenyl]urea

IUPAC name

3-(4-bromo-3-methylphenyl)-1-[4-({5-methyl-[124]triazolo[15-a]pyrimidin-7-yl}sulfanyl)phenyl]urea

SMILES

Cc(cc(cc1)NC(Nc(cc2)ccc2Sc2cc(C)nc3ncnn23)=O)c1Br

InChI

InChI=1S/C20H17BrN6OS/c1-12-9-15(5-8-17(12)21)26-20(28)25-14-3-6-16(7-4-14)29-18-10-13(2)24-19-22-11-23-27(18)19/h3-11H,1-2H3,(H2,25,26,28)

InChI Key

CJTUSEMAQQCXGF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15122645

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

469.36

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

5.284

Distribution Coefficient, logD

5.284

Water Solubility, LogSw

-5.19

Polar Surface Area

64.052

Acid Dissociation Constant (pKa)

12.01

Base Dissociation Constant (pKb)

3.09

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

10.00

L282-0052 in Drug Discovery

Included in Screening Libraries

Serine Proteases Inhibitors Library (32732 compounds)

Targeted Diversity Library (40567 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • Proteases
  • Phosphatases

References: we are preparing a list of scientific research reports with L282-0052 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L282-0052?
Check Price and Availability of L282-0052, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L282-0052 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L282-0052
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L282-0052
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L282-0052 available by request