L282-0247 Screening compound: 3-(5-chloro-2-methylphenyl)-1-[4-({5-propyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl}sulfanyl)phenyl]urea

L282-0247 Screening compound: 3-(5-chloro-2-methylphenyl)-1-[4-({5-propyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl}sulfanyl)phenyl]urea
L282-0247 Screening compound: 3-(5-chloro-2-methylphenyl)-1-[4-({5-propyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl}sulfanyl)phenyl]urea alternative view

Chemical Structure Depiction of ChemDiv screening compound L282-0247
3-(5-chloro-2-methylphenyl)-1-[4-({5-propyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl}sulfanyl)phenyl]urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L282-0247

Molecular Formula

C22H21ClN6OS (C22 H21 ClN6 OS)

Compound Name

3-(5-chloro-2-methylphenyl)-1-[4-({5-propyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl}sulfanyl)phenyl]urea

IUPAC name

3-(5-chloro-2-methylphenyl)-1-[4-({5-propyl-[124]triazolo[15-a]pyrimidin-7-yl}sulfanyl)phenyl]urea

SMILES

CCCc1nc2ncnn2c(Sc(cc2)ccc2NC(Nc2c(C)ccc(Cl)c2)=O)c1

InChI

InChI=1S/C22H21ClN6OS/c1-3-4-17-12-20(29-21(26-17)24-13-25-29)31-18-9-7-16(8-10-18)27-22(30)28-19-11-15(23)6-5-14(19)2/h5-13H,3-4H2,1-2H3,(H2,27,28,30)

InChI Key

MRCDVDLQTPMPMV-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15122696

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

452.97

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

5.808

Distribution Coefficient, logD

5.808

Water Solubility, LogSw

-5.86

Polar Surface Area

64.043

Acid Dissociation Constant (pKa)

11.51

Base Dissociation Constant (pKb)

3.23

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

18.20

L282-0247 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • Proteases
  • Phosphatases

References: we are preparing a list of scientific research reports with L282-0247 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L282-0247?
Check Price and Availability of L282-0247, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L282-0247 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L282-0247
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L282-0247
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L282-0247 available by request