L282-0273 Screening compound: 3-(2,3-dihydro-1,4-benzodioxin-6-yl)-1-[4-({5-propyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl}sulfanyl)phenyl]urea

L282-0273 Screening compound: 3-(2,3-dihydro-1,4-benzodioxin-6-yl)-1-[4-({5-propyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl}sulfanyl)phenyl]urea
L282-0273 Screening compound: 3-(2,3-dihydro-1,4-benzodioxin-6-yl)-1-[4-({5-propyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl}sulfanyl)phenyl]urea alternative view

Chemical Structure Depiction of ChemDiv screening compound L282-0273
3-(2,3-dihydro-1,4-benzodioxin-6-yl)-1-[4-({5-propyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl}sulfanyl)phenyl]urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L282-0273

Molecular Formula

C23H22N6O3S (C23 H22 N6 O3 S)

Compound Name

3-(2,3-dihydro-1,4-benzodioxin-6-yl)-1-[4-({5-propyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl}sulfanyl)phenyl]urea

IUPAC name

n/a

SMILES

CCCc1nc2ncnn2c(Sc(cc2)ccc2NC(Nc(cc2)cc3c2OCCO3)=O)c1

InChI

InChI=1S/C23H22N6O3S/c1-2-3-16-13-21(29-22(26-16)24-14-25-29)33-18-7-4-15(5-8-18)27-23(30)28-17-6-9-19-20(12-17)32-11-10-31-19/h4-9,12-14H,2-3,10-11H2,1H3,(H2,27,28,30)

InChI Key

OIIRYXMOZLQQJL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27239680

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

462.53

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

4.322

Distribution Coefficient, logD

4.322

Water Solubility, LogSw

-4.28

Polar Surface Area

80.564

Acid Dissociation Constant (pKa)

12.33

Base Dissociation Constant (pKb)

3.23

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

21.70

L282-0273 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Angiogenesis library (14822 compounds)

Anticancer Library (62698 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Targeted Diversity Library (40567 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Proteases
Agro:
  • Agro

References: we are preparing a list of scientific research reports with L282-0273 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L282-0273?
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What is the minimum amount of L282-0273 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L282-0273
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L282-0273
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L282-0273 available by request