L282-0767 Screening compound: 1-[4-({5-ethyl-2-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl}sulfanyl)phenyl]-3-[3-(methylsulfanyl)phenyl]urea

L282-0767 Screening compound: 1-[4-({5-ethyl-2-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl}sulfanyl)phenyl]-3-[3-(methylsulfanyl)phenyl]urea
L282-0767 Screening compound: 1-[4-({5-ethyl-2-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl}sulfanyl)phenyl]-3-[3-(methylsulfanyl)phenyl]urea alternative view

Chemical Structure Depiction of ChemDiv screening compound L282-0767
1-[4-({5-ethyl-2-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl}sulfanyl)phenyl]-3-[3-(methylsulfanyl)phenyl]urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L282-0767

Molecular Formula

C22H22N6OS2 (C22 H22 N6 OS2)

Compound Name

1-[4-({5-ethyl-2-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl}sulfanyl)phenyl]-3-[3-(methylsulfanyl)phenyl]urea

IUPAC name

1-[4-({5-ethyl-2-methyl-[124]triazolo[15-a]pyrimidin-7-yl}sulfanyl)phenyl]-3-[3-(methylsulfanyl)phenyl]urea

SMILES

CCc1nc2nc(C)nn2c(Sc(cc2)ccc2NC(Nc2cc(SC)ccc2)=O)c1

InChI

InChI=1S/C22H22N6OS2/c1-4-15-13-20(28-21(24-15)23-14(2)27-28)31-18-10-8-16(9-11-18)25-22(29)26-17-6-5-7-19(12-17)30-3/h5-13H,4H2,1-3H3,(H2,25,26,29)

InChI Key

YDJVWOHJTJXOGJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15122726

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

450.59

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

5.369

Distribution Coefficient, logD

5.369

Water Solubility, LogSw

-5.35

Polar Surface Area

63.413

Acid Dissociation Constant (pKa)

13.45

Base Dissociation Constant (pKb)

3.68

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

18.20

L282-0767 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Immunological Library (6760 compounds)

Regenerative Medicine Focused Library (23016 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Immune system
  • Musculoskeletal
  • Digestive system
  • Hemic and lymphatic
  • Cardiovascular
  • Skin
  • wounds
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • Proteases
  • Phosphatases

References: we are preparing a list of scientific research reports with L282-0767 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L282-0767?
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What is the minimum amount of L282-0767 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L282-0767
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L282-0767
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L282-0767 available by request