L283-0072 Screening compound: 4-bromo-N-[4-({5,6-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl}sulfanyl)phenyl]benzene-1-sulfonamide

L283-0072 Screening compound: 4-bromo-N-[4-({5,6-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl}sulfanyl)phenyl]benzene-1-sulfonamide
L283-0072 Screening compound: 4-bromo-N-[4-({5,6-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl}sulfanyl)phenyl]benzene-1-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L283-0072
4-bromo-N-[4-({5,6-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl}sulfanyl)phenyl]benzene-1-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L283-0072

Molecular Formula

C19H16BrN5O2S2 (C19 H16 BrN5 O2 S2)

Compound Name

4-bromo-N-[4-({5,6-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl}sulfanyl)phenyl]benzene-1-sulfonamide

IUPAC name

4-bromo-N-[4-({56-dimethyl-[124]triazolo[15-a]pyrimidin-7-yl}sulfanyl)phenyl]benzene-1-sulfonamide

SMILES

Cc(c(C)nc1ncnn11)c1Sc(cc1)ccc1NS(c(cc1)ccc1Br)(=O)=O

InChI

InChI=1S/C19H16BrN5O2S2/c1-12-13(2)23-19-21-11-22-25(19)18(12)28-16-7-5-15(6-8-16)24-29(26,27)17-9-3-14(20)4-10-17/h3-11,24H,1-2H3

InChI Key

GBBSIXUSILAAMP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15122734

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

490.4

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.644

Distribution Coefficient, logD

4.584

Water Solubility, LogSw

-4.43

Polar Surface Area

72.945

Acid Dissociation Constant (pKa)

8.23

Base Dissociation Constant (pKb)

3.54

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

10.50

L283-0072 in Drug Discovery

Included in Screening Libraries

Angiogenesis library (14822 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

C-Met Library (15277 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Kinases
  • Proteases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L283-0072 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L283-0072?
Check Price and Availability of L283-0072, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L283-0072 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L283-0072
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L283-0072
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L283-0072 available by request