L283-0265 Screening compound: N-[4-({5-methyl-6-propyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl}sulfanyl)phenyl]-5,6,7,8-tetrahydronaphthalene-2-sulfonamide

L283-0265 Screening compound: N-[4-({5-methyl-6-propyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl}sulfanyl)phenyl]-5,6,7,8-tetrahydronaphthalene-2-sulfonamide
L283-0265 Screening compound: N-[4-({5-methyl-6-propyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl}sulfanyl)phenyl]-5,6,7,8-tetrahydronaphthalene-2-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L283-0265
N-[4-({5-methyl-6-propyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl}sulfanyl)phenyl]-5,6,7,8-tetrahydronaphthalene-2-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L283-0265

Molecular Formula

C25H27N5O2S2 (C25 H27 N5 O2 S2)

Compound Name

N-[4-({5-methyl-6-propyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl}sulfanyl)phenyl]-5,6,7,8-tetrahydronaphthalene-2-sulfonamide

IUPAC name

N-[4-({5-methyl-6-propyl-[124]triazolo[15-a]pyrimidin-7-yl}sulfanyl)phenyl]-5678-tetrahydronaphthalene-2-sulfonamide

SMILES

CCCc(c(C)nc1ncnn11)c1Sc(cc1)ccc1NS(c1cc(CCCC2)c2cc1)(=O)=O

InChI

InChI=1S/C25H27N5O2S2/c1-3-6-23-17(2)28-25-26-16-27-30(25)24(23)33-21-12-10-20(11-13-21)29-34(31,32)22-14-9-18-7-4-5-8-19(18)15-22/h9-16,29H,3-8H2,1-2H3

InChI Key

BKTQOSCUPDSLPN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15122765

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

493.65

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

6.118

Distribution Coefficient, logD

6.094

Water Solubility, LogSw

-5.53

Polar Surface Area

72.866

Acid Dissociation Constant (pKa)

8.65

Base Dissociation Constant (pKb)

3.71

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

32.00

L283-0265 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

C-Met Library (15277 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Kinases
  • Proteases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L283-0265 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L283-0265?
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What is the minimum amount of L283-0265 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L283-0265
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L283-0265
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L283-0265 available by request