L283-0266 Screening compound: 3,4-dimethoxy-N-[4-({5-methyl-6-propyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl}sulfanyl)phenyl]benzene-1-sulfonamide

L283-0266 Screening compound: 3,4-dimethoxy-N-[4-({5-methyl-6-propyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl}sulfanyl)phenyl]benzene-1-sulfonamide
L283-0266 Screening compound: 3,4-dimethoxy-N-[4-({5-methyl-6-propyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl}sulfanyl)phenyl]benzene-1-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L283-0266
3,4-dimethoxy-N-[4-({5-methyl-6-propyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl}sulfanyl)phenyl]benzene-1-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L283-0266

Molecular Formula

C23H25N5O4S2 (C23 H25 N5 O4 S2)

Compound Name

3,4-dimethoxy-N-[4-({5-methyl-6-propyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl}sulfanyl)phenyl]benzene-1-sulfonamide

IUPAC name

34-dimethoxy-N-[4-({5-methyl-6-propyl-[124]triazolo[15-a]pyrimidin-7-yl}sulfanyl)phenyl]benzene-1-sulfonamide

SMILES

CCCc(c(C)nc1ncnn11)c1Sc(cc1)ccc1NS(c(cc1)cc(OC)c1OC)(=O)=O

InChI

InChI=1S/C23H25N5O4S2/c1-5-6-19-15(2)26-23-24-14-25-28(23)22(19)33-17-9-7-16(8-10-17)27-34(29,30)18-11-12-20(31-3)21(13-18)32-4/h7-14,27H,5-6H2,1-4H3

InChI Key

WXOJPSUEZWFRNB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15122766

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

499.61

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

4.383

Distribution Coefficient, logD

4.382

Water Solubility, LogSw

-4.41

Polar Surface Area

88.206

Acid Dissociation Constant (pKa)

10.16

Base Dissociation Constant (pKb)

3.71

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

26.10

L283-0266 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Anticancer Library (62698 compounds)

Antifungal Library (16415 compounds)

Antimitotic Tubulin Library (17355 compounds)

C-Met Library (15277 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Infections
  • Immune system
  • animal
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Agro:
  • Agro
Targets:
  • Kinases
  • Proteases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L283-0266 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L283-0266?
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What is the minimum amount of L283-0266 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L283-0266
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L283-0266
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L283-0266 available by request