L283-0267 Screening compound: 3,4-dimethyl-N-[4-({5-methyl-6-propyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl}sulfanyl)phenyl]benzene-1-sulfonamide

L283-0267 Screening compound: 3,4-dimethyl-N-[4-({5-methyl-6-propyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl}sulfanyl)phenyl]benzene-1-sulfonamide
L283-0267 Screening compound: 3,4-dimethyl-N-[4-({5-methyl-6-propyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl}sulfanyl)phenyl]benzene-1-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L283-0267
3,4-dimethyl-N-[4-({5-methyl-6-propyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl}sulfanyl)phenyl]benzene-1-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L283-0267

Molecular Formula

C23H25N5O2S2 (C23 H25 N5 O2 S2)

Compound Name

3,4-dimethyl-N-[4-({5-methyl-6-propyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl}sulfanyl)phenyl]benzene-1-sulfonamide

IUPAC name

34-dimethyl-N-[4-({5-methyl-6-propyl-[124]triazolo[15-a]pyrimidin-7-yl}sulfanyl)phenyl]benzene-1-sulfonamide

SMILES

CCCc(c(C)nc1ncnn11)c1Sc(cc1)ccc1NS(c1cc(C)c(C)cc1)(=O)=O

InChI

InChI=1S/C23H25N5O2S2/c1-5-6-21-17(4)26-23-24-14-25-28(23)22(21)31-19-10-8-18(9-11-19)27-32(29,30)20-12-7-15(2)16(3)13-20/h7-14,27H,5-6H2,1-4H3

InChI Key

AGVGOVYDKGVWLP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15122767

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

467.62

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

5.802

Distribution Coefficient, logD

5.778

Water Solubility, LogSw

-5.56

Polar Surface Area

72.945

Acid Dissociation Constant (pKa)

8.65

Base Dissociation Constant (pKb)

3.71

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

26.10

L283-0267 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Anticancer Library (62698 compounds)

C-Met Library (15277 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Kinases
  • Proteases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L283-0267 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L283-0267?
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What is the minimum amount of L283-0267 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L283-0267
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L283-0267
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L283-0267 available by request