L283-0281 Screening compound: N-[4-({5-methyl-6-propyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl}sulfanyl)phenyl]-4-(2-methylpropyl)benzene-1-sulfonamide

L283-0281 Screening compound: N-[4-({5-methyl-6-propyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl}sulfanyl)phenyl]-4-(2-methylpropyl)benzene-1-sulfonamide
L283-0281 Screening compound: N-[4-({5-methyl-6-propyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl}sulfanyl)phenyl]-4-(2-methylpropyl)benzene-1-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L283-0281
N-[4-({5-methyl-6-propyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl}sulfanyl)phenyl]-4-(2-methylpropyl)benzene-1-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L283-0281

Molecular Formula

C25H29N5O2S2 (C25 H29 N5 O2 S2)

Compound Name

N-[4-({5-methyl-6-propyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl}sulfanyl)phenyl]-4-(2-methylpropyl)benzene-1-sulfonamide

IUPAC name

N-[4-({5-methyl-6-propyl-[124]triazolo[15-a]pyrimidin-7-yl}sulfanyl)phenyl]-4-(2-methylpropyl)benzene-1-sulfonamide

SMILES

CCCc(c(C)nc1ncnn11)c1Sc(cc1)ccc1NS(c1ccc(CC(C)C)cc1)(=O)=O

InChI

InChI=1S/C25H29N5O2S2/c1-5-6-23-18(4)28-25-26-16-27-30(25)24(23)33-21-11-9-20(10-12-21)29-34(31,32)22-13-7-19(8-14-22)15-17(2)3/h7-14,16-17,29H,5-6,15H2,1-4H3

InChI Key

ABQGYXQSTXEVLB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15122770

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

495.67

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

6.553

Distribution Coefficient, logD

6.529

Water Solubility, LogSw

-5.82

Polar Surface Area

72.945

Acid Dissociation Constant (pKa)

8.65

Base Dissociation Constant (pKb)

3.71

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

32.00

L283-0281 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

C-Met Library (15277 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Kinases
  • Proteases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L283-0281 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L283-0281?
Check Price and Availability of L283-0281, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L283-0281 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L283-0281
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L283-0281
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L283-0281 available by request