L283-0287 Screening compound: N-[4-({5-methyl-6-propyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl}sulfanyl)phenyl]-4-(propan-2-yl)benzene-1-sulfonamide

L283-0287 Screening compound: N-[4-({5-methyl-6-propyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl}sulfanyl)phenyl]-4-(propan-2-yl)benzene-1-sulfonamide
L283-0287 Screening compound: N-[4-({5-methyl-6-propyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl}sulfanyl)phenyl]-4-(propan-2-yl)benzene-1-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L283-0287
N-[4-({5-methyl-6-propyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl}sulfanyl)phenyl]-4-(propan-2-yl)benzene-1-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L283-0287

Molecular Formula

C24H27N5O2S2 (C24 H27 N5 O2 S2)

Compound Name

N-[4-({5-methyl-6-propyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl}sulfanyl)phenyl]-4-(propan-2-yl)benzene-1-sulfonamide

IUPAC name

N-[4-({5-methyl-6-propyl-[124]triazolo[15-a]pyrimidin-7-yl}sulfanyl)phenyl]-4-(propan-2-yl)benzene-1-sulfonamide

SMILES

CCCc(c(C)nc1ncnn11)c1Sc(cc1)ccc1NS(c1ccc(C(C)C)cc1)(=O)=O

InChI

InChI=1S/C24H27N5O2S2/c1-5-6-22-17(4)27-24-25-15-26-29(24)23(22)32-20-11-9-19(10-12-20)28-33(30,31)21-13-7-18(8-14-21)16(2)3/h7-16,28H,5-6H2,1-4H3

InChI Key

DCGSPHZSJKZWGF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15122773

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

481.64

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

6.211

Distribution Coefficient, logD

6.187

Water Solubility, LogSw

-5.70

Polar Surface Area

72.945

Acid Dissociation Constant (pKa)

8.65

Base Dissociation Constant (pKb)

3.71

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

29.20

L283-0287 in Drug Discovery

Included in Screening Libraries

C-Met Library (15277 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Kinases
  • Proteases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L283-0287 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L283-0287?
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What is the minimum amount of L283-0287 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L283-0287
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L283-0287
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L283-0287 available by request