L284-0087 Screening compound: 1-{[1,2-dimethyl-5-(4-phenyl-1,3-thiazol-2-yl)-1H-pyrrol-3-yl]sulfonyl}-1,2,3,4-tetrahydroquinoline

L284-0087 Screening compound: 1-{[1,2-dimethyl-5-(4-phenyl-1,3-thiazol-2-yl)-1H-pyrrol-3-yl]sulfonyl}-1,2,3,4-tetrahydroquinoline
L284-0087 Screening compound: 1-{[1,2-dimethyl-5-(4-phenyl-1,3-thiazol-2-yl)-1H-pyrrol-3-yl]sulfonyl}-1,2,3,4-tetrahydroquinoline alternative view

Chemical Structure Depiction of ChemDiv screening compound L284-0087
1-{[1,2-dimethyl-5-(4-phenyl-1,3-thiazol-2-yl)-1H-pyrrol-3-yl]sulfonyl}-1,2,3,4-tetrahydroquinoline

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L284-0087

Molecular Formula

C24H23N3O2S2 (C24 H23 N3 O2 S2)

Compound Name

1-{[1,2-dimethyl-5-(4-phenyl-1,3-thiazol-2-yl)-1H-pyrrol-3-yl]sulfonyl}-1,2,3,4-tetrahydroquinoline

IUPAC name

1-{[12-dimethyl-5-(4-phenyl-13-thiazol-2-yl)-1H-pyrrol-3-yl]sulfonyl}-1234-tetrahydroquinoline

SMILES

Cc(n(C)c(-c1nc(-c2ccccc2)cs1)c1)c1S(N(CCC1)c2c1cccc2)(=O)=O

InChI

InChI=1S/C24H23N3O2S2/c1-17-23(31(28,29)27-14-8-12-19-11-6-7-13-21(19)27)15-22(26(17)2)24-25-20(16-30-24)18-9-4-3-5-10-18/h3-7,9-11,13,15-16H,8,12,14H2,1-2H3

InChI Key

SNMVJVLXKJZQOY-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27239761

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

449.6

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.170

Distribution Coefficient, logD

5.170

Water Solubility, LogSw

-5.06

Polar Surface Area

42.886

Acid Dissociation Constant (pKa)

24.92

Base Dissociation Constant (pKb)

0.67

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

20.80

L284-0087 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Cardiovascular Library (22201 compounds)

GPCR Targeted Library (31838 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Cardiovascular
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L284-0087 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L284-0087?
Check Price and Availability of L284-0087, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L284-0087 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L284-0087
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L284-0087
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L284-0087 available by request