L284-0308 Screening compound: 1,2-dimethyl-N-[2-(3-methylthiophen-2-yl)ethyl]-5-(4-phenyl-1,3-thiazol-2-yl)-1H-pyrrole-3-sulfonamide

L284-0308 Screening compound: 1,2-dimethyl-N-[2-(3-methylthiophen-2-yl)ethyl]-5-(4-phenyl-1,3-thiazol-2-yl)-1H-pyrrole-3-sulfonamide
L284-0308 Screening compound: 1,2-dimethyl-N-[2-(3-methylthiophen-2-yl)ethyl]-5-(4-phenyl-1,3-thiazol-2-yl)-1H-pyrrole-3-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L284-0308
1,2-dimethyl-N-[2-(3-methylthiophen-2-yl)ethyl]-5-(4-phenyl-1,3-thiazol-2-yl)-1H-pyrrole-3-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L284-0308

Molecular Formula

C22H23N3O2S3 (C22 H23 N3 O2 S3)

Compound Name

1,2-dimethyl-N-[2-(3-methylthiophen-2-yl)ethyl]-5-(4-phenyl-1,3-thiazol-2-yl)-1H-pyrrole-3-sulfonamide

IUPAC name

12-dimethyl-N-[2-(3-methylthiophen-2-yl)ethyl]-5-(4-phenyl-13-thiazol-2-yl)-1H-pyrrole-3-sulfonamide

SMILES

Cc1c(CCNS(c2c(C)n(C)c(-c3nc(-c4ccccc4)cs3)c2)(=O)=O)scc1

InChI

InChI=1S/C22H23N3O2S3/c1-15-10-12-28-20(15)9-11-23-30(26,27)21-13-19(25(3)16(21)2)22-24-18(14-29-22)17-7-5-4-6-8-17/h4-8,10,12-14,23H,9,11H2,1-3H3

InChI Key

WDTHVUPPDXVRLX-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27239800

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

457.64

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.505

Distribution Coefficient, logD

5.504

Water Solubility, LogSw

-5.45

Polar Surface Area

54.351

Acid Dissociation Constant (pKa)

10.51

Base Dissociation Constant (pKb)

0.21

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

22.70

L284-0308 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L284-0308 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L284-0308?
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What is the minimum amount of L284-0308 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L284-0308
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L284-0308
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L284-0308 available by request