L284-1202 Screening compound: 5-[4-(4-fluorophenyl)-1,3-thiazol-2-yl]-1,2-dimethyl-N-(pyridin-3-yl)-1H-pyrrole-3-sulfonamide

L284-1202 Screening compound: 5-[4-(4-fluorophenyl)-1,3-thiazol-2-yl]-1,2-dimethyl-N-(pyridin-3-yl)-1H-pyrrole-3-sulfonamide
L284-1202 Screening compound: 5-[4-(4-fluorophenyl)-1,3-thiazol-2-yl]-1,2-dimethyl-N-(pyridin-3-yl)-1H-pyrrole-3-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L284-1202
5-[4-(4-fluorophenyl)-1,3-thiazol-2-yl]-1,2-dimethyl-N-(pyridin-3-yl)-1H-pyrrole-3-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L284-1202

Molecular Formula

C20H17FN4O2S2 (C20 H17 FN4 O2 S2)

Compound Name

5-[4-(4-fluorophenyl)-1,3-thiazol-2-yl]-1,2-dimethyl-N-(pyridin-3-yl)-1H-pyrrole-3-sulfonamide

IUPAC name

5-[4-(4-fluorophenyl)-13-thiazol-2-yl]-12-dimethyl-N-(pyridin-3-yl)-1H-pyrrole-3-sulfonamide

SMILES

Cc(n(C)c(-c1nc(-c(cc2)ccc2F)cs1)c1)c1S(Nc1cnccc1)(=O)=O

InChI

InChI=1S/C20H17FN4O2S2/c1-13-19(29(26,27)24-16-4-3-9-22-11-16)10-18(25(13)2)20-23-17(12-28-20)14-5-7-15(21)8-6-14/h3-12,24H,1-2H3

InChI Key

DMKDBXWXKOYTAG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27239846

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

428.51

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.031

Distribution Coefficient, logD

4.001

Water Solubility, LogSw

-3.86

Polar Surface Area

61.901

Acid Dissociation Constant (pKa)

8.96

Base Dissociation Constant (pKb)

6.04

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

10.00

L284-1202 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

PI3K-Targeted Library (17255 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with L284-1202 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L284-1202?
Check Price and Availability of L284-1202, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L284-1202 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L284-1202
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L284-1202
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L284-1202 available by request