L284-1296 Screening compound: 1-({5-[4-(4-fluorophenyl)-1,3-thiazol-2-yl]-1,2-dimethyl-1H-pyrrol-3-yl}sulfonyl)-4-phenyl-1,2,3,6-tetrahydropyridine

L284-1296 Screening compound: 1-({5-[4-(4-fluorophenyl)-1,3-thiazol-2-yl]-1,2-dimethyl-1H-pyrrol-3-yl}sulfonyl)-4-phenyl-1,2,3,6-tetrahydropyridine
L284-1296 Screening compound: 1-({5-[4-(4-fluorophenyl)-1,3-thiazol-2-yl]-1,2-dimethyl-1H-pyrrol-3-yl}sulfonyl)-4-phenyl-1,2,3,6-tetrahydropyridine alternative view

Chemical Structure Depiction of ChemDiv screening compound L284-1296
1-({5-[4-(4-fluorophenyl)-1,3-thiazol-2-yl]-1,2-dimethyl-1H-pyrrol-3-yl}sulfonyl)-4-phenyl-1,2,3,6-tetrahydropyridine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L284-1296

Molecular Formula

C26H24FN3O2S2 (C26 H24 FN3 O2 S2)

Compound Name

1-({5-[4-(4-fluorophenyl)-1,3-thiazol-2-yl]-1,2-dimethyl-1H-pyrrol-3-yl}sulfonyl)-4-phenyl-1,2,3,6-tetrahydropyridine

IUPAC name

1-({5-[4-(4-fluorophenyl)-13-thiazol-2-yl]-12-dimethyl-1H-pyrrol-3-yl}sulfonyl)-4-phenyl-1236-tetrahydropyridine

SMILES

Cc(n(C)c(-c1nc(-c(cc2)ccc2F)cs1)c1)c1S(N(CC1)CC=C1c1ccccc1)(=O)=O

InChI

InChI=1S/C26H24FN3O2S2/c1-18-25(34(31,32)30-14-12-20(13-15-30)19-6-4-3-5-7-19)16-24(29(18)2)26-28-23(17-33-26)21-8-10-22(27)11-9-21/h3-12,16-17H,13-15H2,1-2H3

InChI Key

UVUUYWRATVGWNR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27239868

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

493.63

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

6.153

Distribution Coefficient, logD

6.153

Water Solubility, LogSw

-5.67

Polar Surface Area

43.173

Acid Dissociation Constant (pKa)

28.15

Base Dissociation Constant (pKb)

-0.31

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

19.20

L284-1296 in Drug Discovery

Included in Screening Libraries

DGK Inhibitors Library (10558 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Hemic and lymphatic
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with L284-1296 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L284-1296?
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What is the minimum amount of L284-1296 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L284-1296
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L284-1296
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L284-1296 available by request