L284-1980 Screening compound: 5-[4-(3-chlorophenyl)-1,3-thiazol-2-yl]-1,2-dimethyl-N-(5-methylpyridin-2-yl)-1H-pyrrole-3-sulfonamide

L284-1980 Screening compound: 5-[4-(3-chlorophenyl)-1,3-thiazol-2-yl]-1,2-dimethyl-N-(5-methylpyridin-2-yl)-1H-pyrrole-3-sulfonamide
L284-1980 Screening compound: 5-[4-(3-chlorophenyl)-1,3-thiazol-2-yl]-1,2-dimethyl-N-(5-methylpyridin-2-yl)-1H-pyrrole-3-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L284-1980
5-[4-(3-chlorophenyl)-1,3-thiazol-2-yl]-1,2-dimethyl-N-(5-methylpyridin-2-yl)-1H-pyrrole-3-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L284-1980

Molecular Formula

C21H19ClN4O2S2 (C21 H19 ClN4 O2 S2)

Compound Name

5-[4-(3-chlorophenyl)-1,3-thiazol-2-yl]-1,2-dimethyl-N-(5-methylpyridin-2-yl)-1H-pyrrole-3-sulfonamide

IUPAC name

5-[4-(3-chlorophenyl)-13-thiazol-2-yl]-12-dimethyl-N-(5-methylpyridin-2-yl)-1H-pyrrole-3-sulfonamide

SMILES

Cc(n(C)c(-c1nc(-c2cccc(Cl)c2)cs1)c1)c1S(Nc1ncc(C)cc1)(=O)=O

InChI

InChI=1S/C21H19ClN4O2S2/c1-13-7-8-20(23-11-13)25-30(27,28)19-10-18(26(3)14(19)2)21-24-17(12-29-21)15-5-4-6-16(22)9-15/h4-12H,1-3H3,(H,23,25)

InChI Key

JCRMYQOLEVEVPJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27239896

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

458.99

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.239

Distribution Coefficient, logD

4.912

Water Solubility, LogSw

-5.74

Polar Surface Area

62.087

Acid Dissociation Constant (pKa)

7.35

Base Dissociation Constant (pKb)

2.55

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

14.30

L284-1980 in Drug Discovery

Included in Screening Libraries

Protein Kinases Inhibitors Library (36801 compounds)

Type II Kinase Inhibitors Library (6956 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Digestive system
  • Hemic and lymphatic
  • Endocrine
Targets:
  • Kinases
  • Kinases

References: we are preparing a list of scientific research reports with L284-1980 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L284-1980?
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What is the minimum amount of L284-1980 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L284-1980
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L284-1980
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L284-1980 available by request