L284-2114 Screening compound: 5-[4-(3-chlorophenyl)-1,3-thiazol-2-yl]-1,2-dimethyl-N-[(thiophen-2-yl)methyl]-1H-pyrrole-3-sulfonamide

L284-2114 Screening compound: 5-[4-(3-chlorophenyl)-1,3-thiazol-2-yl]-1,2-dimethyl-N-[(thiophen-2-yl)methyl]-1H-pyrrole-3-sulfonamide
L284-2114 Screening compound: 5-[4-(3-chlorophenyl)-1,3-thiazol-2-yl]-1,2-dimethyl-N-[(thiophen-2-yl)methyl]-1H-pyrrole-3-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L284-2114
5-[4-(3-chlorophenyl)-1,3-thiazol-2-yl]-1,2-dimethyl-N-[(thiophen-2-yl)methyl]-1H-pyrrole-3-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L284-2114

Molecular Formula

C20H18ClN3O2S3 (C20 H18 ClN3 O2 S3)

Compound Name

5-[4-(3-chlorophenyl)-1,3-thiazol-2-yl]-1,2-dimethyl-N-[(thiophen-2-yl)methyl]-1H-pyrrole-3-sulfonamide

IUPAC name

5-[4-(3-chlorophenyl)-13-thiazol-2-yl]-12-dimethyl-N-[(thiophen-2-yl)methyl]-1H-pyrrole-3-sulfonamide

SMILES

Cc(n(C)c(-c1nc(-c2cccc(Cl)c2)cs1)c1)c1S(NCc1cccs1)(=O)=O

InChI

InChI=1S/C20H18ClN3O2S3/c1-13-19(29(25,26)22-11-16-7-4-8-27-16)10-18(24(13)2)20-23-17(12-28-20)14-5-3-6-15(21)9-14/h3-10,12,22H,11H2,1-2H3

InChI Key

NKCPTGJCGKNYBY-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27239918

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

464.03

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.376

Distribution Coefficient, logD

5.372

Water Solubility, LogSw

-5.97

Polar Surface Area

54.510

Acid Dissociation Constant (pKa)

9.48

Base Dissociation Constant (pKb)

0.21

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

15.00

L284-2114 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with L284-2114 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L284-2114?
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What is the minimum amount of L284-2114 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L284-2114
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L284-2114
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L284-2114 available by request