L284-2418 Screening compound: 1,2-dimethyl-5-(4-methyl-1,3-thiazol-2-yl)-N-(4-sulfamoylphenyl)-1H-pyrrole-3-sulfonamide

L284-2418 Screening compound: 1,2-dimethyl-5-(4-methyl-1,3-thiazol-2-yl)-N-(4-sulfamoylphenyl)-1H-pyrrole-3-sulfonamide
L284-2418 Screening compound: 1,2-dimethyl-5-(4-methyl-1,3-thiazol-2-yl)-N-(4-sulfamoylphenyl)-1H-pyrrole-3-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L284-2418
1,2-dimethyl-5-(4-methyl-1,3-thiazol-2-yl)-N-(4-sulfamoylphenyl)-1H-pyrrole-3-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L284-2418

Molecular Formula

C16H18N4O4S3 (C16 H18 N4 O4 S3)

Compound Name

1,2-dimethyl-5-(4-methyl-1,3-thiazol-2-yl)-N-(4-sulfamoylphenyl)-1H-pyrrole-3-sulfonamide

IUPAC name

12-dimethyl-5-(4-methyl-13-thiazol-2-yl)-N-(4-sulfamoylphenyl)-1H-pyrrole-3-sulfonamide

SMILES

Cc1csc(-c2cc(S(Nc(cc3)ccc3S(N)(=O)=O)(=O)=O)c(C)n2C)n1

InChI

InChI=1S/C16H18N4O4S3/c1-10-9-25-16(18-10)14-8-15(11(2)20(14)3)27(23,24)19-12-4-6-13(7-5-12)26(17,21)22/h4-9,19H,1-3H3,(H2,17,21,22)

InChI Key

ULPZQVNAZRFICP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27239968

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

426.54

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

1.551

Distribution Coefficient, logD

0.958

Water Solubility, LogSw

-2.38

Polar Surface Area

103.064

Acid Dissociation Constant (pKa)

6.94

Base Dissociation Constant (pKb)

2.89

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

18.80

L284-2418 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Carbonic Anhydrase II Library (4939 compounds)

SH2 PTB Focused Library (6188 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with L284-2418 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L284-2418?
Check Price and Availability of L284-2418, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L284-2418 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L284-2418
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L284-2418
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L284-2418 available by request