L285-1649 Screening compound: 4-({6-[4-methyl-3-(morpholine-4-sulfonyl)phenyl]pyridazin-3-yl}amino)benzene-1-sulfonamide

L285-1649 Screening compound: 4-({6-[4-methyl-3-(morpholine-4-sulfonyl)phenyl]pyridazin-3-yl}amino)benzene-1-sulfonamide
L285-1649 Screening compound: 4-({6-[4-methyl-3-(morpholine-4-sulfonyl)phenyl]pyridazin-3-yl}amino)benzene-1-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L285-1649
4-({6-[4-methyl-3-(morpholine-4-sulfonyl)phenyl]pyridazin-3-yl}amino)benzene-1-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L285-1649

Molecular Formula

C21H23N5O5S2 (C21 H23 N5 O5 S2)

Compound Name

4-({6-[4-methyl-3-(morpholine-4-sulfonyl)phenyl]pyridazin-3-yl}amino)benzene-1-sulfonamide

IUPAC name

4-({6-[4-methyl-3-(morpholine-4-sulfonyl)phenyl]pyridazin-3-yl}amino)benzene-1-sulfonamide

SMILES

Cc(ccc(-c(cc1)nnc1Nc(cc1)ccc1S(N)(=O)=O)c1)c1S(N1CCOCC1)(=O)=O

InChI

InChI=1S/C21H23N5O5S2/c1-15-2-3-16(14-20(15)33(29,30)26-10-12-31-13-11-26)19-8-9-21(25-24-19)23-17-4-6-18(7-5-17)32(22,27)28/h2-9,14H,10-13H2,1H3,(H,23,25)(H2,22,27,28)

InChI Key

AMDPLAZVYDHGKG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27240231

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

489.58

Hydrogen Bond Acceptors Count

13.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

1.969

Distribution Coefficient, logD

1.968

Water Solubility, LogSw

-2.70

Polar Surface Area

121.412

Acid Dissociation Constant (pKa)

10.01

Base Dissociation Constant (pKb)

3.86

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

23.80

L285-1649 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein-Protein Interaction Library (218420 compounds)

Targeted Diversity Library (40567 compounds)

Carbonic Anhydrase II Library (4939 compounds)

SH2 PTB Focused Library (6188 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with L285-1649 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L285-1649?
Check Price and Availability of L285-1649, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L285-1649 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L285-1649
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L285-1649
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L285-1649 available by request