L286-0437 Screening compound: N-(2,4-difluorophenyl)-2-methyl-5-[5-(piperidine-1-carbonyl)-1,2,4-oxadiazol-3-yl]benzene-1-sulfonamide

L286-0437 Screening compound: N-(2,4-difluorophenyl)-2-methyl-5-[5-(piperidine-1-carbonyl)-1,2,4-oxadiazol-3-yl]benzene-1-sulfonamide
L286-0437 Screening compound: N-(2,4-difluorophenyl)-2-methyl-5-[5-(piperidine-1-carbonyl)-1,2,4-oxadiazol-3-yl]benzene-1-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L286-0437
N-(2,4-difluorophenyl)-2-methyl-5-[5-(piperidine-1-carbonyl)-1,2,4-oxadiazol-3-yl]benzene-1-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L286-0437

Molecular Formula

C21H20F2N4O4S (C21 H20 F2 N4 O4 S)

Compound Name

N-(2,4-difluorophenyl)-2-methyl-5-[5-(piperidine-1-carbonyl)-1,2,4-oxadiazol-3-yl]benzene-1-sulfonamide

IUPAC name

N-(24-difluorophenyl)-2-methyl-5-[5-(piperidine-1-carbonyl)-124-oxadiazol-3-yl]benzene-1-sulfonamide

SMILES

Cc(ccc(-c1noc(C(N2CCCCC2)=O)n1)c1)c1S(Nc(ccc(F)c1)c1F)(=O)=O

InChI

InChI=1S/C21H20F2N4O4S/c1-13-5-6-14(19-24-20(31-25-19)21(28)27-9-3-2-4-10-27)11-18(13)32(29,30)26-17-8-7-15(22)12-16(17)23/h5-8,11-12,26H,2-4,9-10H2,1H3

InChI Key

QFUCGNPNEMDCFQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27240496

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

462.48

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.220

Distribution Coefficient, logD

1.476

Water Solubility, LogSw

-4.13

Polar Surface Area

88.516

Acid Dissociation Constant (pKa)

4.66

Base Dissociation Constant (pKb)

-2.78

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

28.60

L286-0437 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with L286-0437 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L286-0437?
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What is the minimum amount of L286-0437 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L286-0437
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L286-0437
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L286-0437 available by request