L286-1360 Screening compound: N-(4-fluoro-2-methylphenyl)-2-methyl-5-[5-(morpholine-4-carbonyl)-1,2,4-oxadiazol-3-yl]benzene-1-sulfonamide

L286-1360 Screening compound: N-(4-fluoro-2-methylphenyl)-2-methyl-5-[5-(morpholine-4-carbonyl)-1,2,4-oxadiazol-3-yl]benzene-1-sulfonamide
L286-1360 Screening compound: N-(4-fluoro-2-methylphenyl)-2-methyl-5-[5-(morpholine-4-carbonyl)-1,2,4-oxadiazol-3-yl]benzene-1-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L286-1360
N-(4-fluoro-2-methylphenyl)-2-methyl-5-[5-(morpholine-4-carbonyl)-1,2,4-oxadiazol-3-yl]benzene-1-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L286-1360

Molecular Formula

C21H21FN4O5S (C21 H21 FN4 O5 S)

Compound Name

N-(4-fluoro-2-methylphenyl)-2-methyl-5-[5-(morpholine-4-carbonyl)-1,2,4-oxadiazol-3-yl]benzene-1-sulfonamide

IUPAC name

N-(4-fluoro-2-methylphenyl)-2-methyl-5-[5-(morpholine-4-carbonyl)-124-oxadiazol-3-yl]benzene-1-sulfonamide

SMILES

Cc(ccc(-c1noc(C(N2CCOCC2)=O)n1)c1)c1S(Nc(cc1)c(C)cc1F)(=O)=O

InChI

InChI=1S/C21H21FN4O5S/c1-13-3-4-15(19-23-20(31-24-19)21(27)26-7-9-30-10-8-26)12-18(13)32(28,29)25-17-6-5-16(22)11-14(17)2/h3-6,11-12,25H,7-10H2,1-2H3

InChI Key

CTKGXCDJBACIIA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27240625

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

460.49

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

3.218

Distribution Coefficient, logD

2.088

Water Solubility, LogSw

-3.41

Polar Surface Area

96.424

Acid Dissociation Constant (pKa)

6.30

Base Dissociation Constant (pKb)

-4.64

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

28.60

L286-1360 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

PI3K-Targeted Library (17255 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with L286-1360 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L286-1360?
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What is the minimum amount of L286-1360 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L286-1360
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L286-1360
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L286-1360 available by request