L286-1743 Screening compound: 5-[5-(azepane-1-carbonyl)-1,2,4-oxadiazol-3-yl]-N-(4-chloro-2-fluorophenyl)-2-methylbenzene-1-sulfonamide

L286-1743 Screening compound: 5-[5-(azepane-1-carbonyl)-1,2,4-oxadiazol-3-yl]-N-(4-chloro-2-fluorophenyl)-2-methylbenzene-1-sulfonamide
L286-1743 Screening compound: 5-[5-(azepane-1-carbonyl)-1,2,4-oxadiazol-3-yl]-N-(4-chloro-2-fluorophenyl)-2-methylbenzene-1-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L286-1743
5-[5-(azepane-1-carbonyl)-1,2,4-oxadiazol-3-yl]-N-(4-chloro-2-fluorophenyl)-2-methylbenzene-1-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L286-1743

Molecular Formula

C22H22ClFN4O4S (C22 H22 ClFN4 O4 S)

Compound Name

5-[5-(azepane-1-carbonyl)-1,2,4-oxadiazol-3-yl]-N-(4-chloro-2-fluorophenyl)-2-methylbenzene-1-sulfonamide

IUPAC name

5-[5-(azepane-1-carbonyl)-124-oxadiazol-3-yl]-N-(4-chloro-2-fluorophenyl)-2-methylbenzene-1-sulfonamide

SMILES

Cc(ccc(-c1noc(C(N2CCCCCC2)=O)n1)c1)c1S(Nc(ccc(Cl)c1)c1F)(=O)=O

InChI

InChI=1S/C22H22ClFN4O4S/c1-14-6-7-15(12-19(14)33(30,31)27-18-9-8-16(23)13-17(18)24)20-25-21(32-26-20)22(29)28-10-4-2-3-5-11-28/h6-9,12-13,27H,2-5,10-11H2,1H3

InChI Key

LTNAQKFVVZMKKL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27240685

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

492.96

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

5.422

Distribution Coefficient, logD

2.677

Water Solubility, LogSw

-5.88

Polar Surface Area

88.847

Acid Dissociation Constant (pKa)

4.66

Base Dissociation Constant (pKb)

-1.78

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

31.80

L286-1743 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with L286-1743 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L286-1743?
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What is the minimum amount of L286-1743 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L286-1743
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L286-1743
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L286-1743 available by request