L287-0451 Screening compound: 4-(5-ethyl-1,2,4-oxadiazol-3-yl)-N-(3-fluorophenyl)thiophene-2-sulfonamide

L287-0451 Screening compound: 4-(5-ethyl-1,2,4-oxadiazol-3-yl)-N-(3-fluorophenyl)thiophene-2-sulfonamide
L287-0451 Screening compound: 4-(5-ethyl-1,2,4-oxadiazol-3-yl)-N-(3-fluorophenyl)thiophene-2-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L287-0451
4-(5-ethyl-1,2,4-oxadiazol-3-yl)-N-(3-fluorophenyl)thiophene-2-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L287-0451

Molecular Formula

C14H12FN3O3S2 (C14 H12 FN3 O3 S2)

Compound Name

4-(5-ethyl-1,2,4-oxadiazol-3-yl)-N-(3-fluorophenyl)thiophene-2-sulfonamide

IUPAC name

4-(5-ethyl-124-oxadiazol-3-yl)-N-(3-fluorophenyl)thiophene-2-sulfonamide

SMILES

CCc1nc(-c2csc(S(Nc3cc(F)ccc3)(=O)=O)c2)no1

InChI

InChI=1S/C14H12FN3O3S2/c1-2-12-16-14(17-21-12)9-6-13(22-8-9)23(19,20)18-11-5-3-4-10(15)7-11/h3-8,18H,2H2,1H3

InChI Key

CPMUGONCDMLDJD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27240712

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

353.4

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.905

Distribution Coefficient, logD

3.801

Water Solubility, LogSw

-3.96

Polar Surface Area

73.249

Acid Dissociation Constant (pKa)

7.97

Base Dissociation Constant (pKb)

-2.61

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

14.30

L287-0451 in Drug Discovery

Included in Screening Libraries

NOTUM (Wnt signaling) Library (3881 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with L287-0451 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L287-0451?
Check Price and Availability of L287-0451, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L287-0451 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L287-0451
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L287-0451
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L287-0451 available by request