L287-0828 Screening compound: N-cyclopentyl-4-(5-cyclopropyl-1,2,4-oxadiazol-3-yl)-2-thiophenesulfonamide

L287-0828 Screening compound: N-cyclopentyl-4-(5-cyclopropyl-1,2,4-oxadiazol-3-yl)-2-thiophenesulfonamide
L287-0828 Screening compound: N-cyclopentyl-4-(5-cyclopropyl-1,2,4-oxadiazol-3-yl)-2-thiophenesulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L287-0828
N-cyclopentyl-4-(5-cyclopropyl-1,2,4-oxadiazol-3-yl)-2-thiophenesulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L287-0828

Molecular Formula

C14H17N3O3S2 (C14 H17 N3 O3 S2)

Compound Name

N-cyclopentyl-4-(5-cyclopropyl-1,2,4-oxadiazol-3-yl)-2-thiophenesulfonamide

IUPAC name

N-cyclopentyl-4-(5-cyclopropyl-124-oxadiazol-3-yl)thiophene-2-sulfonamide

SMILES

O=S(c1cc(-c2noc(C3CC3)n2)cs1)(NC1CCCC1)=O

InChI

InChI=1S/C14H17N3O3S2/c18-22(19,17-11-3-1-2-4-11)12-7-10(8-21-12)13-15-14(20-16-13)9-5-6-9/h7-9,11,17H,1-6H2

InChI Key

YDSZVCKGGPLLHV-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27240745

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

339.44

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.762

Distribution Coefficient, logD

3.761

Water Solubility, LogSw

-3.92

Polar Surface Area

75.249

Acid Dissociation Constant (pKa)

10.08

Base Dissociation Constant (pKb)

-1.44

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

57.14

L287-0828 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Targeted Diversity Library (40567 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • GPCR
  • Kinases
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L287-0828 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L287-0828?
Check Price and Availability of L287-0828, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L287-0828 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L287-0828
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L287-0828
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L287-0828 available by request