L287-1254 Screening compound: N-[(2H-1,3-benzodioxol-5-yl)methyl]-4-(5-cyclobutyl-1,2,4-oxadiazol-3-yl)thiophene-2-sulfonamide

L287-1254 Screening compound: N-[(2H-1,3-benzodioxol-5-yl)methyl]-4-(5-cyclobutyl-1,2,4-oxadiazol-3-yl)thiophene-2-sulfonamide
L287-1254 Screening compound: N-[(2H-1,3-benzodioxol-5-yl)methyl]-4-(5-cyclobutyl-1,2,4-oxadiazol-3-yl)thiophene-2-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L287-1254
N-[(2H-1,3-benzodioxol-5-yl)methyl]-4-(5-cyclobutyl-1,2,4-oxadiazol-3-yl)thiophene-2-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L287-1254

Molecular Formula

C18H17N3O5S2 (C18 H17 N3 O5 S2)

Compound Name

N-[(2H-1,3-benzodioxol-5-yl)methyl]-4-(5-cyclobutyl-1,2,4-oxadiazol-3-yl)thiophene-2-sulfonamide

IUPAC name

N-[(2H-13-benzodioxol-5-yl)methyl]-4-(5-cyclobutyl-124-oxadiazol-3-yl)thiophene-2-sulfonamide

SMILES

O=S(c1cc(-c2noc(C3CCC3)n2)cs1)(NCc(cc1)cc2c1OCO2)=O

InChI

InChI=1S/C18H17N3O5S2/c22-28(23,19-8-11-4-5-14-15(6-11)25-10-24-14)16-7-13(9-27-16)17-20-18(26-21-17)12-2-1-3-12/h4-7,9,12,19H,1-3,8,10H2

InChI Key

CFAUKLHEKDKKQR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27240811

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

419.48

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.762

Distribution Coefficient, logD

3.761

Water Solubility, LogSw

-3.94

Polar Surface Area

92.059

Acid Dissociation Constant (pKa)

9.90

Base Dissociation Constant (pKb)

-2.38

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

33.30

L287-1254 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with L287-1254 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L287-1254?
Check Price and Availability of L287-1254, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L287-1254 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L287-1254
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L287-1254
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L287-1254 available by request