L287-1362 Screening compound: 4-(5-cyclobutyl-1,2,4-oxadiazol-3-yl)-N-[4-(trifluoromethoxy)phenyl]thiophene-2-sulfonamide

L287-1362 Screening compound: 4-(5-cyclobutyl-1,2,4-oxadiazol-3-yl)-N-[4-(trifluoromethoxy)phenyl]thiophene-2-sulfonamide
L287-1362 Screening compound: 4-(5-cyclobutyl-1,2,4-oxadiazol-3-yl)-N-[4-(trifluoromethoxy)phenyl]thiophene-2-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L287-1362
4-(5-cyclobutyl-1,2,4-oxadiazol-3-yl)-N-[4-(trifluoromethoxy)phenyl]thiophene-2-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L287-1362

Molecular Formula

C17H14F3N3O4S2 (C17 H14 F3 N3 O4 S2)

Compound Name

4-(5-cyclobutyl-1,2,4-oxadiazol-3-yl)-N-[4-(trifluoromethoxy)phenyl]thiophene-2-sulfonamide

IUPAC name

4-(5-cyclobutyl-124-oxadiazol-3-yl)-N-[4-(trifluoromethoxy)phenyl]thiophene-2-sulfonamide

SMILES

O=S(c1cc(-c2noc(C3CCC3)n2)cs1)(Nc(cc1)ccc1OC(F)(F)F)=O

InChI

InChI=1S/C17H14F3N3O4S2/c18-17(19,20)26-13-6-4-12(5-7-13)23-29(24,25)14-8-11(9-28-14)15-21-16(27-22-15)10-2-1-3-10/h4-10,23H,1-3H2

InChI Key

KDHAPQMXWMMMNU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27240855

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

445.44

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

5.324

Distribution Coefficient, logD

5.321

Water Solubility, LogSw

-5.66

Polar Surface Area

79.772

Acid Dissociation Constant (pKa)

9.52

Base Dissociation Constant (pKb)

-1.93

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

29.40

L287-1362 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
Agro:
  • Agro

References: we are preparing a list of scientific research reports with L287-1362 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L287-1362?
Check Price and Availability of L287-1362, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L287-1362 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L287-1362
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L287-1362
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L287-1362 available by request