L287-1648 Screening compound: 5-cyclopentyl-3-[5-(pyrrolidine-1-sulfonyl)thiophen-3-yl]-1,2,4-oxadiazole

L287-1648 Screening compound: 5-cyclopentyl-3-[5-(pyrrolidine-1-sulfonyl)thiophen-3-yl]-1,2,4-oxadiazole
L287-1648 Screening compound: 5-cyclopentyl-3-[5-(pyrrolidine-1-sulfonyl)thiophen-3-yl]-1,2,4-oxadiazole alternative view

Chemical Structure Depiction of ChemDiv screening compound L287-1648
5-cyclopentyl-3-[5-(pyrrolidine-1-sulfonyl)thiophen-3-yl]-1,2,4-oxadiazole

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L287-1648

Molecular Formula

C15H19N3O3S2 (C15 H19 N3 O3 S2)

Compound Name

5-cyclopentyl-3-[5-(pyrrolidine-1-sulfonyl)thiophen-3-yl]-1,2,4-oxadiazole

IUPAC name

5-cyclopentyl-3-[5-(pyrrolidine-1-sulfonyl)thiophen-3-yl]-124-oxadiazole

SMILES

O=S(c1cc(-c2noc(C3CCCC3)n2)cs1)(N1CCCC1)=O

InChI

InChI=1S/C15H19N3O3S2/c19-23(20,18-7-3-4-8-18)13-9-12(10-22-13)14-16-15(21-17-14)11-5-1-2-6-11/h9-11H,1-8H2

InChI Key

GYBNVTJNYNZRRH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27240901

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

353.47

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.875

Distribution Coefficient, logD

3.875

Water Solubility, LogSw

-3.82

Polar Surface Area

65.298

Acid Dissociation Constant (pKa)

26.07

Base Dissociation Constant (pKb)

-2.18

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

60.00

L287-1648 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS MPO Library (28609 compounds)

GPCR Targeted Library (31838 compounds)

SmartTM Library (51161 compounds)

Targeted Diversity Library (40567 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • GPCR
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L287-1648 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L287-1648?
Check Price and Availability of L287-1648, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L287-1648 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L287-1648
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L287-1648
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L287-1648 available by request