L287-1684 Screening compound: 4-(5-cyclopentyl-1,2,4-oxadiazol-3-yl)-2-thienyl (4-methylpiperazino) sulfone

L287-1684 Screening compound: 4-(5-cyclopentyl-1,2,4-oxadiazol-3-yl)-2-thienyl (4-methylpiperazino) sulfone
L287-1684 Screening compound: 4-(5-cyclopentyl-1,2,4-oxadiazol-3-yl)-2-thienyl (4-methylpiperazino) sulfone alternative view

Chemical Structure Depiction of ChemDiv screening compound L287-1684
4-(5-cyclopentyl-1,2,4-oxadiazol-3-yl)-2-thienyl (4-methylpiperazino) sulfone

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L287-1684

Molecular Formula

C16H22N4O3S2 (C16 H22 N4 O3 S2)

Compound Name

4-(5-cyclopentyl-1,2,4-oxadiazol-3-yl)-2-thienyl (4-methylpiperazino) sulfone

IUPAC name

1-{[4-(5-cyclopentyl-124-oxadiazol-3-yl)thiophen-2-yl]sulfonyl}-4-methylpiperazine

SMILES

CN(CC1)CCN1S(c1cc(-c2noc(C3CCCC3)n2)cs1)(=O)=O

InChI

InChI=1S/C16H22N4O3S2/c1-19-6-8-20(9-7-19)25(21,22)14-10-13(11-24-14)15-17-16(23-18-15)12-4-2-3-5-12/h10-12H,2-9H2,1H3

InChI Key

MQMDLUIDSBFFRA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27240919

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

382.51

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.110

Distribution Coefficient, logD

3.021

Water Solubility, LogSw

-3.12

Polar Surface Area

68.408

Acid Dissociation Constant (pKa)

26.07

Base Dissociation Constant (pKb)

6.75

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

62.50

L287-1684 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

SmartTM Library (51161 compounds)

Targeted Diversity Library (40567 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with L287-1684 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L287-1684?
Check Price and Availability of L287-1684, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L287-1684 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L287-1684
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L287-1684
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L287-1684 available by request