L287-2418 Screening compound: 1-{[4-(5-cyclobutyl-1,2,4-oxadiazol-3-yl)thiophen-2-yl]sulfonyl}-4-cyclopropanecarbonylpiperazine

L287-2418 Screening compound: 1-{[4-(5-cyclobutyl-1,2,4-oxadiazol-3-yl)thiophen-2-yl]sulfonyl}-4-cyclopropanecarbonylpiperazine
L287-2418 Screening compound: 1-{[4-(5-cyclobutyl-1,2,4-oxadiazol-3-yl)thiophen-2-yl]sulfonyl}-4-cyclopropanecarbonylpiperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound L287-2418
1-{[4-(5-cyclobutyl-1,2,4-oxadiazol-3-yl)thiophen-2-yl]sulfonyl}-4-cyclopropanecarbonylpiperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L287-2418

Molecular Formula

C18H22N4O4S2 (C18 H22 N4 O4 S2)

Compound Name

1-{[4-(5-cyclobutyl-1,2,4-oxadiazol-3-yl)thiophen-2-yl]sulfonyl}-4-cyclopropanecarbonylpiperazine

IUPAC name

1-{[4-(5-cyclobutyl-124-oxadiazol-3-yl)thiophen-2-yl]sulfonyl}-4-cyclopropanecarbonylpiperazine

SMILES

O=C(C1CC1)N(CC1)CCN1S(c1cc(-c2noc(C3CCC3)n2)cs1)(=O)=O

InChI

InChI=1S/C18H22N4O4S2/c23-18(13-4-5-13)21-6-8-22(9-7-21)28(24,25)15-10-14(11-27-15)16-19-17(26-20-16)12-2-1-3-12/h10-13H,1-9H2

InChI Key

HFQNBPJFRFTISP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27240980

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

422.53

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.615

Distribution Coefficient, logD

2.615

Water Solubility, LogSw

-2.81

Polar Surface Area

81.876

Acid Dissociation Constant (pKa)

22.91

Base Dissociation Constant (pKb)

-1.42

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

61.10

L287-2418 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

SmartTM Library (51161 compounds)

Targeted Diversity Library (40567 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with L287-2418 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L287-2418?
Check Price and Availability of L287-2418, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L287-2418 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L287-2418
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L287-2418
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L287-2418 available by request