L287-2439 Screening compound: 1-{[4-(5-cyclobutyl-1,2,4-oxadiazol-3-yl)thiophen-2-yl]sulfonyl}-4-(3-methylbenzoyl)piperazine

L287-2439 Screening compound: 1-{[4-(5-cyclobutyl-1,2,4-oxadiazol-3-yl)thiophen-2-yl]sulfonyl}-4-(3-methylbenzoyl)piperazine
L287-2439 Screening compound: 1-{[4-(5-cyclobutyl-1,2,4-oxadiazol-3-yl)thiophen-2-yl]sulfonyl}-4-(3-methylbenzoyl)piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound L287-2439
1-{[4-(5-cyclobutyl-1,2,4-oxadiazol-3-yl)thiophen-2-yl]sulfonyl}-4-(3-methylbenzoyl)piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L287-2439

Molecular Formula

C22H24N4O4S2 (C22 H24 N4 O4 S2)

Compound Name

1-{[4-(5-cyclobutyl-1,2,4-oxadiazol-3-yl)thiophen-2-yl]sulfonyl}-4-(3-methylbenzoyl)piperazine

IUPAC name

1-{[4-(5-cyclobutyl-124-oxadiazol-3-yl)thiophen-2-yl]sulfonyl}-4-(3-methylbenzoyl)piperazine

SMILES

Cc1cccc(C(N(CC2)CCN2S(c2cc(-c3noc(C4CCC4)n3)cs2)(=O)=O)=O)c1

InChI

InChI=1S/C22H24N4O4S2/c1-15-4-2-7-17(12-15)22(27)25-8-10-26(11-9-25)32(28,29)19-13-18(14-31-19)20-23-21(30-24-20)16-5-3-6-16/h2,4,7,12-14,16H,3,5-6,8-11H2,1H3

InChI Key

LLKMIVFCCZUCGS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27240984

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

472.59

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.462

Distribution Coefficient, logD

3.462

Water Solubility, LogSw

-3.56

Polar Surface Area

81.353

Acid Dissociation Constant (pKa)

26.82

Base Dissociation Constant (pKb)

-2.38

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

40.90

L287-2439 in Drug Discovery

Included in Screening Libraries

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • Phosphatases

References: we are preparing a list of scientific research reports with L287-2439 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L287-2439?
Check Price and Availability of L287-2439, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L287-2439 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L287-2439
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L287-2439
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L287-2439 available by request