L287-2476 Screening compound: 6-(4-{[4-(5-cyclobutyl-1,2,4-oxadiazol-3-yl)thiophen-2-yl]sulfonyl}piperazine-1-carbonyl)-1H-indole

L287-2476 Screening compound: 6-(4-{[4-(5-cyclobutyl-1,2,4-oxadiazol-3-yl)thiophen-2-yl]sulfonyl}piperazine-1-carbonyl)-1H-indole
L287-2476 Screening compound: 6-(4-{[4-(5-cyclobutyl-1,2,4-oxadiazol-3-yl)thiophen-2-yl]sulfonyl}piperazine-1-carbonyl)-1H-indole alternative view

Chemical Structure Depiction of ChemDiv screening compound L287-2476
6-(4-{[4-(5-cyclobutyl-1,2,4-oxadiazol-3-yl)thiophen-2-yl]sulfonyl}piperazine-1-carbonyl)-1H-indole

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L287-2476

Molecular Formula

C23H23N5O4S2 (C23 H23 N5 O4 S2)

Compound Name

6-(4-{[4-(5-cyclobutyl-1,2,4-oxadiazol-3-yl)thiophen-2-yl]sulfonyl}piperazine-1-carbonyl)-1H-indole

IUPAC name

6-(4-{[4-(5-cyclobutyl-124-oxadiazol-3-yl)thiophen-2-yl]sulfonyl}piperazine-1-carbonyl)-1H-indole

SMILES

O=C(c1cc([nH]cc2)c2cc1)N(CC1)CCN1S(c1cc(-c2noc(C3CCC3)n2)cs1)(=O)=O

InChI

InChI=1S/C23H23N5O4S2/c29-23(17-5-4-15-6-7-24-19(15)12-17)27-8-10-28(11-9-27)34(30,31)20-13-18(14-33-20)21-25-22(32-26-21)16-2-1-3-16/h4-7,12-14,16,24H,1-3,8-11H2

InChI Key

ROLYPRQDUIRMKT-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27240994

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

497.6

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

3.485

Distribution Coefficient, logD

3.485

Water Solubility, LogSw

-3.73

Polar Surface Area

91.134

Acid Dissociation Constant (pKa)

17.71

Base Dissociation Constant (pKb)

-2.38

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

34.80

L287-2476 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Indole Derivatives (10091 compounds)

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

Protein-Protein Interaction Library (218420 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

Included in 1.7M Stock Database

Structure:
  • Cyclic compounds
  • Mimetics
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • Receptor's ligands
Therapeutical areas:
  • Immune system

References: we are preparing a list of scientific research reports with L287-2476 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L287-2476?
Check Price and Availability of L287-2476, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L287-2476 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L287-2476
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L287-2476
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L287-2476 available by request