L287-2504 Screening compound: (2E)-1-(4-{[4-(5-cyclobutyl-1,2,4-oxadiazol-3-yl)thiophen-2-yl]sulfonyl}piperazin-1-yl)-3-phenylprop-2-en-1-one

L287-2504 Screening compound: (2E)-1-(4-{[4-(5-cyclobutyl-1,2,4-oxadiazol-3-yl)thiophen-2-yl]sulfonyl}piperazin-1-yl)-3-phenylprop-2-en-1-one
L287-2504 Screening compound: (2E)-1-(4-{[4-(5-cyclobutyl-1,2,4-oxadiazol-3-yl)thiophen-2-yl]sulfonyl}piperazin-1-yl)-3-phenylprop-2-en-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound L287-2504
(2E)-1-(4-{[4-(5-cyclobutyl-1,2,4-oxadiazol-3-yl)thiophen-2-yl]sulfonyl}piperazin-1-yl)-3-phenylprop-2-en-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L287-2504

Molecular Formula

C23H24N4O4S2 (C23 H24 N4 O4 S2)

Compound Name

(2E)-1-(4-{[4-(5-cyclobutyl-1,2,4-oxadiazol-3-yl)thiophen-2-yl]sulfonyl}piperazin-1-yl)-3-phenylprop-2-en-1-one

IUPAC name

(2E)-1-(4-{[4-(5-cyclobutyl-124-oxadiazol-3-yl)thiophen-2-yl]sulfonyl}piperazin-1-yl)-3-phenylprop-2-en-1-one

SMILES

O=C(/C=C/c1ccccc1)N(CC1)CCN1S(c1cc(-c2noc(C3CCC3)n2)cs1)(=O)=O

InChI

InChI=1S/C23H24N4O4S2/c28-20(10-9-17-5-2-1-3-6-17)26-11-13-27(14-12-26)33(29,30)21-15-19(16-32-21)22-24-23(31-25-22)18-7-4-8-18/h1-3,5-6,9-10,15-16,18H,4,7-8,11-14H2

InChI Key

AALXFURYTHKTTK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27240999

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

484.6

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.876

Distribution Coefficient, logD

3.876

Water Solubility, LogSw

-4.06

Polar Surface Area

80.825

Acid Dissociation Constant (pKa)

26.82

Base Dissociation Constant (pKb)

0.47

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

34.80

L287-2504 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Eccentric PPI Library (11937 compounds)

Protein-Protein Interaction Library (218420 compounds)

Covalent Inhibitors Library (7986 compounds)

?ysteine Targeted Covalent Library (39471 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds
  • Cyclic compounds
  • 3D
  • Fragments

References: we are preparing a list of scientific research reports with L287-2504 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L287-2504?
Check Price and Availability of L287-2504, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L287-2504 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L287-2504
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L287-2504
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L287-2504 available by request